Evidence map›Paper›PMID 33431226›Full record

ArticleJournal of diabetes and its complications2021

Associations of diabetes self-management characteristics, HbA1c, and psychosocial outcomes with depressive symptoms in a contemporary sample of adolescents with type 1 diabetes.

Kara R Harrington, Amit Shapira, Lisa K Volkening, Deborah A Butler, Barbara J Anderson, Rachel M Wasserman, Lori M Laffel

Registry-linked trialAbstract read
In one paragraph

Article in Journal of diabetes and its complications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01892280 (Optimizing Self-Management Adherence and Glycemic Control in Older Teens With Type 1 Diabetes), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01892280 nacompletednot on this map

Optimizing Self-Management Adherence and Glycemic Control in Older Teens With Type 1 Diabetes: The Teenwork Study

TypeinterventionalSponsorJoslin Diabetes CenterRan2013 to 2016Enrolled310ConditionsType 1 DiabetesArmsTeenwork intervention, Text message reminders
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kara R HarringtonSection on Clinical, Behavioral, and Outcomes Research, Pediatric, Adolescent, and Young Adult Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, United States of America.
Amit ShapiraSection on Clinical, Behavioral, and Outcomes Research, Pediatric, Adolescent, and Young Adult Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, United States of America.
Lisa K VolkeningSection on Clinical, Behavioral, and Outcomes Research, Pediatric, Adolescent, and Young Adult Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, United States of America.
Deborah A ButlerSection on Clinical, Behavioral, and Outcomes Research, Pediatric, Adolescent, and Young Adult Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, United States of America.
Barbara J AndersonBaylor College of Medicine, Houston, TX, United States of America.
Rachel M WassermanNemours Children's Hospital, Orlando, FL, United States of America.
Lori M LaffelSection on Clinical, Behavioral, and Outcomes Research, Pediatric, Adolescent, and Young Adult Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, United States of America. Electronic address: lori.laffel@joslin.harvard.edu.

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
TRAINING IN DIABETES AND METABOLISMT32DK007260 · NIDDK · JOSLIN DIABETES CENTER · PI LAURIE J GOODYEAR · 1986 to 2026
$13.6M
CAREER DEVELOPMENT IN DIABETES RESEARCH FOR PEDIATRIC ENDOCRINOLOGISTSK12DK094721 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI LAFFEL, LORI M, WHITE, MORRIS F. · 2011 to 2021
$6.3M
Optimizing Self-Management Adherence and Glycemic Control in Older Teens with T1DR01DK095273 · NIDDK · JOSLIN DIABETES CENTER · PI ANDERSON, BARBARA JANE, LAFFEL, LORI M · 2012 to 2015
$2.7M
VESICULAR TRANSPORT IN EPITHELIAL CELLS--ROLE OF ARF6F32DK009472 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI MURRAY, KAREN F · 1996 to 1997
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NIDDK NIH HHS F32 DK009472NIDDK NIH HHS K12 DK094721NIDDK NIH HHS P30 DK036836NIDDK NIH HHS R01 DK095273NIDDK NIH HHS T32 DK007260
6 · The paper itself

Abstract

aimsWe sought to examine the associations between diabetes self-management, HbA1c, and psychosocial outcomes with the frequency of depressive symptoms.

methodsWe surveyed 301 teens (50% male, 22% non-white), mean age of 15.0±1.3 years, diabetes duration of 6.5±3.7 years. Biomedical variables: daily frequency of blood glucose monitoring of 4.5±1.9, 63% insulin pump use, mean HbA1c 8.5±1.1% (69±12 mmol/mol); 15% of the sample achieved the target HbA1c of <7.5% (<58 mmol/mol).

resultsNearly 1 in 5 (18%, n=54) adolescents reported significant depressive symptoms and, of those participants, slightly under half reported moderate/severe depressive symptoms. Teens with moderate/severe depressive symptoms (CES-D scores ≥24) were more likely to be female, have parents without a college education, and not utilize insulin pumps. Teens with more depressive symptoms reported higher diabetes family conflict, higher diabetes burden, and lower quality of life. In the group reporting no depressive symptoms (10%), scores on psychosocial variables and diabetes treatment variables were the most favorable.

conclusionIn our sample, the presence of depressive symptoms appears to relate to both diabetes treatment and quality of life. In addition, studying teens without depressive symptoms can help us learn more about protective factors that potentially buffer against depressive symptoms and that are associated with better outcomes.

Indexed as

DepressionDiabetes Mellitus, Type 1Self-ManagementAdolescentBlood GlucoseBlood Glucose Self-MonitoringFemaleGlycated HemoglobinHumansInsulinsMaleQuality of LifeBlood GlucoseGlycated HemoglobinInsulinsAdolescenceDepressive symptomsType 1 diabetes

Identifiers

PMID33431226
PMCPMC7870579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.