Evidence map›Paper›PMID 33431040›Full record

ArticlePilot and feasibility studies2021

Evaluating a web- and telephone-based personalised exercise intervention for individuals living with metastatic prostate cancer (ExerciseGuide): protocol for a pilot randomised controlled trial.

Holly E L Evans, Cynthia C Forbes, Daniel A Galvão, Corneel Vandelanotte, Robert U Newton, Gary Wittert, Suzanne Chambers, Andrew D Vincent, Ganessan Kichenadasse, Nicholas Brook and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pilot and feasibility studies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Qualitative research exploring the complexities of exercise promotion in prostate cancer survivorship.International journal of qualitative studies on health and well-being · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 2 countries.

Holly E L EvansFreemasons Foundation Centre for Men's Health, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Cynthia C ForbesWolfson Palliative Care Research Centre, Institute of Clinical and Applied Health Research, University of Hull, Hull, United Kingdom.
Daniel A GalvãoExercise Medicine Research Institute, Edith Cowan University, Joondalup, Western Australia, Australia.
Corneel VandelanotteSchool of Health, Medical and Applied Sciences, Appleton Institute, Physical Activity Research Group, Central Queensland University, North Rockhampton, Queensland, Australia.
Robert U NewtonExercise Medicine Research Institute, Edith Cowan University, Joondalup, Western Australia, Australia.
Gary WittertFreemasons Foundation Centre for Men's Health, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Suzanne ChambersFaculty of Health, University of Technology, Sydney, New South Wales, Australia.
Andrew D VincentFreemasons Foundation Centre for Men's Health, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Ganessan KichenadasseCollege of Medicine and Public Health, Flinders Centre for Innovation in Cancer, Bedford Park, South Australia, Australia.
Nicholas BrookDepartment of Surgery, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Danielle GirardAlliance for Research in Exercise, Nutrition and Activity, Allied Health and Human Performance, University of South Australia, Adelaide, South Australia, Australia.
Camille E ShortFreemasons Foundation Centre for Men's Health, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia. Camille.short@unimelb.edu.au.ORCID http://orcid.org/0000-0002-4177-4251
Freemasons Foundation Centre for Men's Health · AUEdith Cowan University · AUCentral Queensland University · AUFlinders University · AUThe University of Adelaide · AUThe University of Melbourne · AUUniversity of Hull · GBUniversity of South Australia · AUUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPreliminary research has shown the effectiveness of supervised exercise-based interventions in alleviating sequela resulting from metastatic prostate cancer. Despite this, many individuals do not engage in sufficient exercise to gain the benefits. There are many barriers, which limit the uptake of face-to-face exercise in this population including lack of suitable facilities, remoteness, and access to experts, significant fatigue, urinary incontinence and motivation. Technology-enabled interventions offer a distance-based alternative. This protocol describes a pilot two-armed randomised controlled study that will investigate the feasibility and preliminary efficacy of an online exercise and behavioural change tool (ExerciseGuide) amongst individuals with metastatic prostate cancer.

methodsSixty-six participants with histologically diagnosed metastatic prostate cancer will be randomised into either the 8-week intervention or a wait-list control. The intervention arm will have access to a tailored website, remote supervision, and tele-coaching sessions to enhance support and adherence. Algorithms will individually prescribe resistance and aerobic exercise based upon factors such as metastasis location, pain, fatigue, confidence and current exercise levels. Behavioural change strategies and education on exercise benefits, safety and lifestyle are also tailored through the website. The primary outcome will be intervention feasibility (safety, usability, acceptability, and adherence). Secondary exploratory outcomes include changes in physical activity, quality of life, sleep, and physical function. Outcomes will be measured at baseline and week 9. DISCUSSION: The study aims to determine the potential feasibility of an online remotely monitored exercise intervention developed for individuals with metastatic prostate cancer. If feasible, this pilot intervention will inform the design and implementation of further distance-based interventions.

trial registrationANZCTR, ACTRN12614001268639 . Registered 10 December 2018, https://anzctr.org.au/ACTRN12618001979246.aspx.

Indexed as

AerobicBehavioural changeComputer tailoringeHealthExerciseMetastatic prostate cancerResistance training

Identifiers

PMID33431040
PMCPMC7798256
OpenAlexW3119585634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.