Evidence map›Paper›PMID 33431027›Full record

ArticlePilot and feasibility studies2021

Technology intervention to support caregiving for Alzheimer's disease (I-CARE): study protocol for a randomized controlled pilot trial.

Tyler Braly, Doris Muriathiri, Janetta C Brown, Britain M Taylor, Malaz A Boustani, Richard J Holden

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pilot and feasibility studies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03119259 (Technology Intervention to Support Caregiving for Alzheimer's Disease), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03119259 nacompletednot on this map

Technology Intervention to Support Caregiving for Alzheimer's Disease (I-CARE)

TypeinterventionalSponsorIndiana UniversityRan2019 to 2021Enrolled53ConditionsDementia, Alzheimer TypeArmsABC Clinical Program, BCN
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. The methodology of the Agile Nudge University.Frontiers in health services · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tyler BralyCenter of Health Innovation and Implementation Science, Indiana Clinical and Translational Sciences Institute, 410 W. 10th St, Indianapolis, IN, 46202, USA.ORCID http://orcid.org/0000-0002-1879-1192
Doris MuriathiriCenter of Health Innovation and Implementation Science, Indiana Clinical and Translational Sciences Institute, 410 W. 10th St, Indianapolis, IN, 46202, USA.
Janetta C BrownCenter of Health Innovation and Implementation Science, Indiana Clinical and Translational Sciences Institute, 410 W. 10th St, Indianapolis, IN, 46202, USA.
Britain M TaylorCenter of Health Innovation and Implementation Science, Indiana Clinical and Translational Sciences Institute, 410 W. 10th St, Indianapolis, IN, 46202, USA.
Malaz A BoustaniCenter of Health Innovation and Implementation Science, Indiana Clinical and Translational Sciences Institute, 410 W. 10th St, Indianapolis, IN, 46202, USA.
Richard J HoldenCenter of Health Innovation and Implementation Science, Indiana Clinical and Translational Sciences Institute, 410 W. 10th St, Indianapolis, IN, 46202, USA. rjholden@iu.edu.

Funding

Technology Intervention to Support Caregiving for Alzheimer's Disease (I-CARE)R21AG062966 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI BOUSTANI, MALAZ, HOLDEN, RICHARD J · 2019 to 2020
$427k
NIA NIH HHS R21 AG062966NIA NIH HHS R21AG062966
6 · The paper itself

Abstract

backgroundInformal caregivers of patients with Alzheimer's disease and related dementias (ADRD) manage a complex spectrum of patient behavioral and psychological symptoms of dementia (BPSD). Mobile health information technologies have quickly become sources for modern social support and chronic disease management. These technologies can improve our understanding of how to care for patients with ADRD and their informal caregivers. A mobile telehealth intervention could help reduce caregiver burden and BPSD.

methodsThis is a pilot randomized controlled trial of 60 dyads of patients living with ADRD and their caregivers, to test the feasibility and estimate the potential effect of the Brain CareNotes (BCN) mobile telehealth system. Participants will be recruited from two health systems. Participants will be randomly assigned to either the BCN intervention arm or usual care comparator. Data will be collected at baseline, 3- and 6-month follow-up. The primary objectives of this trial are to assess feasibility outcomes: (a) recruitment rate, (b) data completion, (c) BCN usability, (d) BCN acceptance, and (e) BCN use and assessed either on an ongoing basis or at 3- and 6-month post-intervention. A secondary objective was to estimate the intervention's effects on caregiver burden and patient BPSD outcomes at 3 and 6 months, assessed by the Neuropsychiatric Inventory. DISCUSSION: The study will assess the intervention feasibility and potential effect size of the BCN telehealth system as a potentially scalable and lower-cost solution for addressing the ADRD public health crisis.

trial registrationClinical Trials. NCT03119259 . Registered on April 18, 2017.

Indexed as

Alzheimer’s diseaseBrain diseasesCentral nervous system diseasesDementiaMental disordersNervous system diseasesNeurocognitive disordersNeurodegenerative diseasesTauopathies

Identifiers

PMID33431027
PMCPMC7798342

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.