ReviewJournal of medical case reports2021
Effective treatment of osmotic demyelination syndrome with plasmapheresis: a case report and review of the literature.
Review in Journal of medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Pitfalls in the management of undiagnosed secondary adrenal insufficiency: a case report and review of the literature.Journal of medical case reports · 2026Review
- Article
- Indications and complications associated with centrifuge-based therapeutic plasma exchange - a retrospective review.BMC nephrology · 2025Article
- Consequences of Hyponatremia: Central Pontine and Extrapontine Myelinolysis in a Chronic Alcohol User.Cureus · 2024Article
- Hand knob sign in osmotic demyelinating syndrome.BMC neurology · 2024Article
- The Response of Osmotic Demyelination Syndrome to Plasmapheresis in a Patient Presenting with Catatonia after Correction of Hyponatraemia in Hyperemesis Gravidarum.European journal of case reports in internal medicine · 2024Article
- Article
- Osmotic demyelination syndrome with transient diabetes insipidus in postpartum female: a case report.Annals of medicine and surgery (2012) · 2023Article
- Case report: Recovery and sequential imaging of a patient with osmotic demyelination syndrome.Frontiers in veterinary science · 2023Article
- Case Report: Osmotic Demyelination Syndrome After Transcatheter Aortic Valve Replacement: Case Report and Review of Current Literature.Frontiers in medicine · 2022Article
- Case Report: Hindlimb Ataxia Concurrent With Seizures by Presumed Osmotic Demyelination Syndrome in a Dog.Frontiers in veterinary science · 2022Article
- Osmotic demyelination syndrome following slow correction of hyponatraemia.BMJ case reports · 2021Article
- Plasmapheresis for Extrapontine Myelinolysis: A Case Series and a Literature Review.Case reports in neurologyArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTreatment options for chronic osmotic demyelination syndrome are limited to case reports and only a very few show complete recovery. We report a case of complete recovery of chronic osmotic demyelination syndrome with plasmapheresis. CASE PRESENTATION: A 43-year-old Sri Lankan man presented with fever, repeated vomiting, unsteady gait, increased tonicity of his right upper limb and paucity of speech for three days. He was treated in the local hospital with antibiotics and antivirals as per central nervous system infection. He had hyponatraemia, which was rapidly corrected with hypertonic saline from 97 to 119 mmol/L. He was transferred to our hospital because of progressive reduction of consciousness, rapidly worsening rigidity and bradykinesia of all four limbs and worsening dysarthria and bradyphrenia. Magnetic resonance imaging of the brain was compatible with osmotic demyelination syndrome. He was commenced on plasmapheresis twenty-two days after rapid correction of sodium. He regained independent mobility with complete resolution of rigidity, bradykinesia and speech dysfunction after five cycles of alternate day plasmapheresis.
conclusionPlasmapheresis can be considered as an effective treatment modality in chronic osmotic demyelination syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.