ArticleAlzheimer's research & therapy2021
Kidney function and dementia risk in community-dwelling older adults: the Shanghai Aging Study.
Article in Alzheimer's research & therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Population attributable fractions of a wide range of peripheral diseases for the burden of dementia.Nature human behaviour · 2026Pooled it
- Transcriptional risk score for chronic kidney disease: relation to Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Association of glymphatic function with 40-Hz neural oscillations, systemic metabolic markers, and cognitive performance in healthy aging adults: An EEG and MRI study.Translational psychiatry · 2026Article
- Article
- Albuminuria is associated with increased risk of dementia, independent of eGFR: The SCREAM project.Journal of internal medicine · 2025Article
- eGFR-ACR Risk Stratification of Rapid Kidney Function Decline Across Aging Phenotypes in Older Chinese Adults.Clinical interventions in aging · 2025Observational
- Association of dementia with impaired kidney function and plasma biomarkers: A population-based study.European journal of neurology · 2024Article
- Renal function and risk of dementia: a Mendelian randomization study.Renal failure · 2024Article
- Association of chronic kidney disease with cognitive impairment risk in middle-aged and older adults: the first longitudinal evidence from CHARLS.Scientific reports · 2024Article
- Significance of plasma p-tau217 in predicting long-term dementia risk in older community residents: Insights from machine learning approaches.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Systemic inflammation in midlife is associated with late-life functional limitations.Scientific reports · 2024Observational
- Mid- and Late-Life Chronic Kidney Disease Is Associated with Parkinson's Disease, Not with an Increased Risk of Alzheimer's Disease.Journal of personalized medicine · 2024Article
- The impact of kidney function on plasma neurofilament light and phospho-tau 181 in a community-based cohort: the Shanghai Aging Study.Alzheimer's research & therapy · 2024Article
- Association of Kidney Function With Dementia and Structural Brain Differences: A Large Population-Based Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Plasma AβClinical kidney journal · 2023Article
- Kidney function, albuminuria, and their modification by genetic factors and risk of incident dementia in UK Biobank.Alzheimer's research & therapy · 2023Article
- Association of impaired kidney function with dementia and brain pathologies: A community-based cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Confounding factors of Alzheimer's disease plasma biomarkers and their impact on clinical performance.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Intra-Brain and Plasma Levels of L-Serine Are Associated with Cognitive Status in Patients with Chronic Kidney Disease.Kidney diseases (Basel, Switzerland) · 2023Article
- Plasma βAlzheimer's research & therapy · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAssociation between kidney dysfunction and dementia has been studied in western cohorts, but with inconsistent conclusions which may be due to the different measurements of kidney function. We aim to verify the hypothesis that lower levels of kidney function would be associated with increased risk of incident dementia in Chinese elderly.
methodsOne thousand four hundred twelve dementia-free participants aged 60 years or older from the Shanghai Aging Study were enrolled and followed up for 5.3 years on average. Glomerular filtration rate (GFR) was calculated by using combined creatinine-cystatin C CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation. Diagnoses of incident dementia and Alzheimer's disease (AD) were established using DSM-IV and NINCDS-ADRDA criteria based on medical, neurological, and neuropsychological examinations to each participant. Cox proportional regression was used to analyze the association of baseline GFR
resultsA total of 113 (8%) and 84 (7%) participants developed dementia and AD. Comparing to participants with high GFR
conclusionsGFR
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