Evidence map›Paper›PMID 33430881›Full record

ReviewWorld journal of surgical oncology2021

COVID-19-induced sarcopenia and physical deconditioning may require reassessment of surgical risk for patients with cancer.

Patrick Casey, Yeng Ang, Javed Sultan

Registry-linked trialOpen access · goldAbstract readLetterReview
In one paragraph

Review in World journal of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05851807 (Intraoperative Lung Mechanics, Postoperative Complications, and Functional Evaluation in Post COVID-19 Patients Undergoing Thoracic Surgery), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05851807 unknown statusnot on this mapstarted 2022, after this paper: background citation

Intraoperative Lung Mechanics, Postoperative Complications, and Functional Evaluation in Post COVID-19 Patients Undergoing Thoracic Surgery

Typeobservational_patient_registrySponsorAnkara UniversityRan2022 to 2024Enrolled120ConditionsCOVID-19 Pandemic, Anesthesia, Thoracic Diseases
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Dysphagia in non-intubated patients affected by COVID-19 infection.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Screening for Sarcopenia (Physical Frailty) in the COVID-19 Era.International journal of endocrinology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Patrick CaseyDepartment of Oeosphagogastric Surgery, Salford Royal Foundation Trust, Salford, UK. Patrick.casey@srft.nhs.uk.ORCID http://orcid.org/0000-0003-1458-1283
Yeng AngDepartment of Oeosphagogastric Surgery, Salford Royal Foundation Trust, Salford, UK.
Javed SultanDepartment of Oeosphagogastric Surgery, Salford Royal Foundation Trust, Salford, UK.
Salford Royal NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe long-term physiological consequences of SARS-CoV-2 (severe acute respiratory syndrome coronavirus) infection are not known. The ability of COVID-19 to cause chronic illness, sarcopenia, and physical deconditioning may be underestimated and go beyond the anticipated respiratory sequelae. Myalgia, lethargy, and anorexia are common symptoms even in mild to moderate cases and have the potential to exacerbate frailty. How this impacts on risk-stratification for patients requiring surgery for time-critical conditions, such as malignancy, requires further urgent investigation. MAIN BODY: The deleterious effect of sarcopenia and poor physical capacity are well recognised in cancer surgery. This review commentary highlights current evidence which suggests skeletal muscle as an under recognised cause of COVID-19-related functional deconditioning. The mechanisms behind this are via direct (viral induced myositis, nutritional decline, cytokine-mediated myopathy) and indirect mechanisms (social isolation, inactivity, and psychological consequences).

conclusionFurther mechanistic research is required to explore the processes behind the deconditioning effects of SARS-CoV-2 infection and how this impacts on treatment of malignant disease.

Indexed as

Physical Functional PerformanceSARS-CoV-2COVID-19HumansMyalgiaNeoplasmsSarcopeniaSurgical Procedures, OperativeCOVID-19FrailtyFunctional deconditioningPrehabilitationSarcopeniaSARS-CoV-2

Identifiers

PMID33430881
PMCPMC7798369
OpenAlexW3119713835

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.