Observational studyBMC pregnancy and childbirth2021
Apgar score and neonatal mortality in China: an observational study from a national surveillance system.
Observational study in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Risk factors associated with birth asphyxia at Pumwani Maternity Hospital, Nairobi, Kenya: a case-control study.Frontiers in pediatrics · 2026Article
- Predicting early and late neonatal mortality using machine learning models in Oman.BMC public health · 2025Article
- Use and implications of the Apgar score in evaluating resuscitation of newborns with birth asphyxia in a lower-middle-income country.Journal of global health · 2025Article
- Early Neonatal Mortality (< 24 h) in Ecuador: A Population-Based Study on the Impact of Apgar Score, Gestational Age, Birth Weight, Delivery Type, and Healthcare Level.International journal of pediatrics · 2025Article
- Perinatal mortality and its predictors in Beni City, Democratic Republic of Congo: a cross-sectional study.Maternal health, neonatology and perinatology · 2024Article
- Smaller babies at risk: birth weight impacts neonatal survival status in Silte zone, Central Ethiopia. A survival analysis of prospective cohort study.Frontiers in pediatrics · 2024Article
- Perinatal outcomes in anemic pregnant women in public hospitals of eastern Ethiopia.International health · 2023Article
- Comparison of the effects of general and spinal anesthesia for cesarean delivery on maternal and fetal outcomes: A retrospective analysis of data.Northern clinics of Istanbul · 2023Article
- Clinical Features and Antibiotic Treatment of Neonatal Listeriosis: A Hospital-Based Study.Infection and drug resistance · 2023Article
- Early outcomes of preterm neonates with respiratory distress syndrome admitted at Muhimbili National Hospital, a prospective study.BMC pediatrics · 2022Article
- Characteristics and fetal outcomes of pregnant women with hypertensive disorders in China: a 9-year national hospital-based cohort study.BMC pregnancy and childbirth · 2022Article
- Considering the Effects and Maternofoetal Implications of Vascular Disorders and the Umbilical Cord.Medicina (Kaunas, Lithuania) · 2022Review
- Apgar scores correlate with survival rate at discharge in extremely preterm infants with gestational age of 25-27 weeks.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022Article
- Time to death and its predictors among neonates who were admitted to the neonatal intensive care unit at tertiary hospital, Addis Ababa, Ethiopia: Retrospective follow up study.Frontiers in pediatrics · 2022Article
- Article
- Determinants for perinatal adverse outcomes among pregnant women with preterm premature rupture of membrane: A prospective cohort study.Frontiers in reproductive health · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundTo examine the association between the Apgar score and neonatal mortality over gestational age in China and to explore whether this association changed when Apgar scores were combined at 1 and 5 min.
methodsData for all singleton live births collected from 438 hospitals between 2012 and 2016 were used in this study. Poisson regression with a robust variance estimator adjusted for a complete set of confounders was used to describe the strength of the association between the Apgar score and neonatal mortality.
resultsThe relative risks of neonatal death-associated intermediate Apgar score at 5 min peaked at 39-40 weeks of gestation and subsequently decreased if the gestational age increased to 42 weeks or above, in contrast to the low Apgar score. Among both preterm and term new-borns with Apgar scores at 5 min, new-borns that were not small for gestational age had a lower mortality rate than those that were small for gestational age. The association between Apgar score and the neonatal mortality was even stronger when scores at 1 and 5 min were combined.
conclusionsApgar score is not only meaningful for preterm new-borns but also useful for term new-borns, especially term new-borns that are not small for gestational age. Once the baby's Apgar score worsens, timely intervention is needed. There is still a gap between China and high-income countries in terms of sustained treatment of new-borns with low Apgar scores.
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