Evidence map›Paper›PMID 33430787›Full record

ArticleBMC microbiology2021

Homology analysis between clinically isolated extraintestinal and enteral Klebsiella pneumoniae among neonates.

Chun-Mei Chen, Min Wang, Xian-Ping Li, Peng-Ling Li, Jing-Jing Tian, Kan Zhang, Can Luo

Erratum issuedOpen access · goldAbstract readComparative Study
In one paragraph

Article in BMC microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  4. ESBL-producingEpidemiology and infection · 2025
    Observational
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  6. Deciphering the gastrointestinal carriage ofInfection and immunity · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chun-Mei ChenDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China.
Min WangDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China. wangmin0000@csu.edu.cn.ORCID 0000-0002-3420-4031
Xian-Ping LiDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China.
Peng-Ling LiDepartment of Laboratory Medicine, Jiangxi Cancer Hospital, Nanchang, Jiangxi, China.
Jing-Jing TianDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China.
Kan ZhangDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China.
Can LuoDepartment of Laboratory Medicine, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China.
Central South University · CNJiangxi Provincial Cancer Hospital · CN

Funding

Hunan Provincial Science and Technology Department 2017SK50122
6 · The paper itself

Abstract

backgroundKlebsiella pneumoniae is a leading cause of hospital-associated (HA) infections. It has been reported that gastrointestinal colonization (GI) is likely to be a common and significant reservoir for the transmission and infections of K. pneumoniae in both adults and neonates. However, the homologous relationship between clinically isolated extraintestinal and enteral K. pneumoniae in neonates hasn't been characterized yet.

resultsForty-three isolates from 21 neonatal patients were collected in this study. The proportion of carbapenem resistance was 62.8%. There were 12 patients (12/21, 57.4%) whose antibiotic resistance phenotypes, genotypes, and ST types (STs) were concordant. Six sequence types were detected using MLST, with ST37 and ST54 being the dominant types. The results of MLST were consist with the results of PFGE.

conclusionsThese data showed that there might be a close homologous relationship between extraintestinal K. pneumoniae (EXKP) and enteral K. pneumoniae (EKP) in neonates, indicating that the K. pneumoniae from the GI tract is possibly to be a significant reservoir for causing extraintestinal infections.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBacterial ProteinsElectrophoresis, Gel, Pulsed-FieldFemaleHumansInfant, NewbornKlebsiella InfectionsKlebsiella pneumoniaeMaleMultilocus Sequence TypingPhenotypePhylogenySequence Analysis, DNAAnti-Bacterial AgentsBacterial ProteinsAntibiotic resistanceEndogenic infectionGastrointestinal colonizationKlebsiella pneumoniaeMultiple locus sequence typing

Identifiers

PMID33430787
PMCPMC7802202
OpenAlexW3114966491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.