ArticleCirculation. Cardiovascular quality and outcomes2021
Microrandomized Trial Design for Evaluating Just-in-Time Adaptive Interventions Through Mobile Health Technologies for Cardiovascular Disease.
Article in Circulation. Cardiovascular quality and outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Integrated Behavioral Interventions for Adults with Comorbid Obesity and Depression: a Systematic Review.Current diabetes reports · 2022Pooled it
- Characteristics of Tailored Text Messages Associated With Increased Physical Activity Among Cardiac Rehabilitation Enrollees: Secondary Analysis of a Microrandomized Trial.JMIR mHealth and uHealth · 2026Trial
- Impact of Push Notifications on Physical Activity and Sodium Intake Among Patients with Hypertension: Microrandomized Trial of a Just-in-Time Adaptive Intervention.Journal of medical Internet research · 2026Trial
- Trial
- Mechanism of an integrated PBL-KAP-AI spiral health education model for breast cancer patients.Frontiers in public health · 2025Trial
- Text Messages to Promote Physical Activity in Patients With Cardiovascular Disease: A Micro-Randomized Trial of a Just-In-Time Adaptive Intervention.Circulation. Cardiovascular quality and outcomes · 2024Trial
- Understanding Heterogeneity in Individual Responses to Digital Lifestyle Intervention Through Self-Monitoring Adherence Trajectories in Adults With Overweight or Obesity: Secondary Analysis of a 6-Month Randomized Controlled Trial.Journal of medical Internet research · 2024Trial
- Acceptability of a Text Message-Based Mobile Health Intervention to Promote Physical Activity in Cardiac Rehabilitation Enrollees: A Qualitative Substudy of Participant Perspectives.Journal of the American Heart Association · 2024Trial
- A bibliometric analysis of research on the application of just-in-time adaptive interventions in mental health.Medicine · 2026Review
- Just-in-Time Adaptive Interventions to Reduce Sedentary Behavior and Promote Physical Activity in Patients With Chronic Disease: Scoping Review.JMIR mHealth and uHealth · 2026Article
- Mobile App-Based Tracking of Daily Explicit and Implicit Sense of Agency Among Adults Living in Japan: Longitudinal Observational Study.JMIR formative research · 2026Observational
- Development and effectiveness evaluation of a mobile health-based follow-up management model for patients after hematopoietic stem cell transplantation.Frontiers in medicine · 2026Article
- WMRE2030: integrating wearable devices, multi-omics, and artificial intelligence-driven real-time feedback into a daily-scale closed-loop framework for a new era of precision exercise.Frontiers in physiology · 2026Review
- Efficacy and acceptability of a blended intervention for emotion regulation (MAISHA) among young people in Kenya: study protocol for a cluster RCT.BMC psychology · 2025Article
- Effectiveness of 2 Just-in-Time Adaptive Interventions for Reducing Stress and Stabilizing Cardiac Autonomic Function: Microrandomized Trials.Journal of medical Internet research · 2025Article
- Role of Mobile Health and Wearable Devices in Cardiovascular Disease Prevention: A Comprehensive Review.Cureus · 2025Review
- Designing digital health interventions with causal inference and multi-armed bandits: a review.Frontiers in digital health · 2025Review
- ReBandit: Random Effects Based Online RL Algorithm for Reducing Cannabis Use.IJCAI : proceedings of the conference · 2024Article
- A Community Participatory Approach to Creating Contextually Tailored mHealth Notifications: myBPmyLife Project.Health promotion practice · 2024Article
- Consolidated guidance for behavioral intervention pilot and feasibility studies.Pilot and feasibility studies · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Smartphone and wearable device use is rising broadly and can be leveraged for chronic disease management. Just-in-time adaptive interventions promise to deliver personalized, dynamic interventions directly to patients through use of push notifications from mobile devices. Although just-in-time adaptive interventions are a powerful tool for shaping health behavior, their application to cardiovascular disease management has been limited as they can be challenging to design. Herein, we provide a general overview and conceptual framework for microrandomized trials, a novel experimental study design that can be used to optimize just-in-time adaptive interventions. Microrandomized trials leverage mobile devices to sequentially randomize participants to types or levels of an intervention to determine the effectiveness of an intervention and time-varying moderators of those effects. Microrandomized trials are an efficient study design that can be used to determine which intervention components to include in just-in-time adaptive interventions and to optimize their decision rules while maintaining the strength of causal inference associated with traditional randomized controlled trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.