Evidence map›Paper›PMID 33430305›Full record

ReviewInternational journal of molecular sciences2021

Lynch Syndrome: Its Impact on Urothelial Carcinoma.

Andrea Katharina Lindner, Gert Schachtner, Gennadi Tulchiner, Martin Thurnher, Gerold Untergasser, Peter Obrist, Iris Pipp, Fabian Steinkohl, Wolfgang Horninger, Zoran Culig and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Genes · 2025
    Article
  5. Article
  6. Article
  7. Pembrolizumab alters the tumor immune landscape in a patient with dMMR glioblastoma.medRxiv : the preprint server for health sciences · 2023
    Article
  8. Bladder cancer.Nature reviews. Disease primers · 2023
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Andrea Katharina LindnerDepartment of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Gert SchachtnerDepartment of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Gennadi TulchinerDepartment of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-2964-1544
Martin ThurnherDepartment of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-9940-7326
Gerold UntergasserDepartment of Internal Medicine V, Medical University Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-3430-119X
Peter ObristPathology Laboratory Obrist and Brunhuber, 6511 Zams, Austria.
Iris PippClinical Pathology and Cytodiagnostics, tirol-kliniken, 6020 Innsbruck, Austria.
Fabian SteinkohlDepartment of Radiology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Wolfgang HorningerDepartment of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Zoran CuligDepartment of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.
Renate PichlerDepartment of Urology, Medical University Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-5286-9048
Innsbruck Medical University · ATTirol Kliniken · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lynch syndrome, known as hereditary nonpolyposis colorectal cancer (HNPCC), is an autosomal-dominant familial cancer syndrome with an increased risk for urothelial cancer (UC). Mismatch repair (MMR) deficiency, due to pathogenic variants in

Indexed as

Genetic Predisposition to DiseaseCarcinomaColorectal Neoplasms, Hereditary NonpolyposisDNA-Binding ProteinsDNA Mismatch RepairHumansMicrosatellite InstabilityMismatch Repair Endonuclease PMS2MutL Protein Homolog 1MutS Homolog 2 ProteinUrotheliumDNA-Binding ProteinsG-T mismatch-binding proteinMismatch Repair Endonuclease PMS2MLH1 protein, humanMSH2 protein, humanMutL Protein Homolog 1MutS Homolog 2 ProteinPMS2 protein, humancheckpoint inhibitorDNA mismatch repair genesimmunotherapyLynch syndromemicrosatellite instabilityMMRupper urinary tracturothelial cancer

Identifiers

PMID33430305
PMCPMC7825811
OpenAlexW3119348748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.