Evidence map›Paper›PMID 33430194›Full record

ArticleBiosensors2021

Development of a Sensitive Self-Powered Glucose Biosensor Based on an Enzymatic Biofuel Cell.

Kantapat Chansaenpak, Anyanee Kamkaew, Sireerat Lisnund, Pannaporn Prachai, Patipat Ratwirunkit, Thitichaya Jingpho, Vincent Blay, Piyanut Pinyou

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Immobilization of Enzyme Cascades with DNA Scaffolds.Methods in molecular biology (Clifton, N.J.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Kantapat ChansaenpakNational Nanotechnology Center, National Science and Technology Development Agency, Thailand Science Park, Pathum Thani 12120, Thailand.
Anyanee KamkaewSchool of Chemistry, Institute of Science, Suranaree University of Technology, 111 University Avenue, Suranaree, Muang, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0003-1203-2686
Sireerat LisnundDepartment of Applied Chemistry, Faculty of Science and Liberal Arts, Rajamangala University of Technology Isan, 744, Suranarai Rd., Nakhon Ratchasima 30000, Thailand.
Pannaporn PrachaiSCiUS, Suranaree University of Technology, 111 University Avenue, Suranaree, Muang, Nakhon Ratchasima 30000, Thailand.
Patipat RatwirunkitSCiUS, Suranaree University of Technology, 111 University Avenue, Suranaree, Muang, Nakhon Ratchasima 30000, Thailand.
Thitichaya JingphoSCiUS, Suranaree University of Technology, 111 University Avenue, Suranaree, Muang, Nakhon Ratchasima 30000, Thailand.
Vincent BlayDivision of Biomaterials and Bioengineering, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA.ORCID 0000-0001-9602-2375
Piyanut PinyouSchool of Chemistry, Institute of Science, Suranaree University of Technology, 111 University Avenue, Suranaree, Muang, Nakhon Ratchasima 30000, Thailand.ORCID 0000-0001-7978-1898
Suranaree University of Technology · THNational Science and Technology Development Agency · THRajamangala University of Technology Isan · THUniversity of California, San Francisco · US

Funding

Generalitat Valenciana APOSTD/2020/120Suranaree University of Technology BRO1-102-62-12-01
6 · The paper itself

Abstract

Biofuel cells allow for constructing sensors that leverage the specificity of enzymes without the need for an external power source. In this work, we design a self-powered glucose sensor based on a biofuel cell. The redox enzymes glucose dehydrogenase (NAD-GDH), glucose oxidase (GOx), and horseradish peroxidase (HRP) were immobilized as biocatalysts on the electrodes, which were previously engineered using carbon nanostructures, including multi-wall carbon nanotubes (MWCNTs) and reduced graphene oxide (rGO). Additional polymers were also introduced to improve biocatalyst immobilization. The reported design offers three main advantages: (i) by using glucose as the substrate for the both anode and cathode, a more compact and robust design is enabled, (ii) the system operates under air-saturating conditions, with no need for gas purge, and (iii) the combination of carbon nanostructures and a multi-enzyme cascade maximizes the sensitivity of the biosensor. Our design allows the reliable detection of glucose in the range of 0.1-7.0 mM, which is perfectly suited for common biofluids and industrial food samples.

Indexed as

BiocatalysisBioelectric Energy SourcesBiosensing TechniquesElectrodesEnzymes, ImmobilizedGlucoseGlucose 1-DehydrogenaseGlucose OxidaseGraphiteHorseradish PeroxidaseNanotubes, CarbonEnzymes, ImmobilizedGlucoseGlucose 1-DehydrogenaseGlucose Oxidasegraphene oxideGraphiteHorseradish PeroxidaseNanotubes, Carbonbiofuel cellbiosensorglucoseglucose oxidasehorseradish peroxidaseNAD-glucose dehydrogenasereduced graphene oxideself-powered

Identifiers

PMID33430194
PMCPMC7825672
OpenAlexW3119965765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.