Evidence map›Paper›PMID 33430187›Full record

ArticlePolymers2021

Initiated Chemical Vapor Deposition (iCVD) Functionalized Polylactic Acid-Marine Algae Composite Patch for Bone Tissue Engineering.

Wiebke Reichstein, Levke Sommer, Salih Veziroglu, Selin Sayin, Stefan Schröder, Yogendra Kumar Mishra, Eyüp İlker Saygili, Fatih Karayürek, Yahya Açil, Jörg Wiltfang and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

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  3. Review
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Wiebke ReichsteinChair for Multicomponent Materials, Institute of Materials Science, Faculty of Engineering, Kiel University, Kaiserstr. 2, 24143 Kiel, Germany.
Levke SommerDepartment of Oral and Maxillofacial Surgery, Campus Kiel, University Hospital of Schleswig-Holstein, Arnold-Heller-Straße 3, 24105 Kiel, Germany.
Salih VezirogluChair for Multicomponent Materials, Institute of Materials Science, Faculty of Engineering, Kiel University, Kaiserstr. 2, 24143 Kiel, Germany.ORCID 0000-0002-1310-6651
Selin SayinMarine Science and Technology Faculty, Iskenderun Technical University, 31200 Iskenderun/Hatay, Turkey.
Stefan SchröderChair for Multicomponent Materials, Institute of Materials Science, Faculty of Engineering, Kiel University, Kaiserstr. 2, 24143 Kiel, Germany.
Yogendra Kumar MishraMads Clausen Institute, NanoSYD, University of Southern Denmark, Alsion 2, 6400 Sønderborg, Denmark.ORCID 0000-0002-8786-9379
Eyüp İlker SaygiliDepartment of Medical Biochemistry, SANKO University, Şehitkamil, 27090 Gaziantep, Turkey.
Fatih KarayürekDepartment of Periodontology, Cankiri Karatekin University, 18100 Cankiri, Turkey.ORCID 0000-0003-0602-7610
Yahya AçilDepartment of Oral and Maxillofacial Surgery, Campus Kiel, University Hospital of Schleswig-Holstein, Arnold-Heller-Straße 3, 24105 Kiel, Germany.
Jörg WiltfangDepartment of Oral and Maxillofacial Surgery, Campus Kiel, University Hospital of Schleswig-Holstein, Arnold-Heller-Straße 3, 24105 Kiel, Germany.
Aydin GülsesDepartment of Oral and Maxillofacial Surgery, Campus Kiel, University Hospital of Schleswig-Holstein, Arnold-Heller-Straße 3, 24105 Kiel, Germany.
Franz FaupelChair for Multicomponent Materials, Institute of Materials Science, Faculty of Engineering, Kiel University, Kaiserstr. 2, 24143 Kiel, Germany.ORCID 0000-0003-3367-1655
Oral Cenk AktasChair for Multicomponent Materials, Institute of Materials Science, Faculty of Engineering, Kiel University, Kaiserstr. 2, 24143 Kiel, Germany.
Hochschule für Angewandte Wissenschaften Kiel · DEChristian-Albrechts-Universität zu Kiel · DEÇankırı Karatekin University · TRİskenderun Technical University · TRSanko University · TRUniversity of Southern Denmark · DK

Funding

Deutsche Forschungsgemeinschaft RTG2154
6 · The paper itself

Abstract

The current study aimed to describe the fabrication of a composite patch by incorporating marine algae powders (MAPs) into poly-lactic acid (PLA) for bone tissue engineering. The prepared composite patch was functionalized with the co-polymer, poly (2-hydroxyethyl methacrylate-co-ethylene glycol dimethacrylate) (p(HEMA-co-EGDMA)) via initiated chemical vapor deposition (iCVD) to improve its wettability and overall biocompatibility. The iCVD functionalized MAP-PLA composite patch showed superior cell interaction of human osteoblasts. Following the surface functionalization by p(HEMA-co-EGDMA) via the iCVD technique, a highly hydrophilic patch was achieved without tailoring any morphological and structural properties. Moreover, the iCVD modified composite patch exhibited ideal cell adhesion for human osteoblasts, thus making the proposed patch suitable for potential biomedical applications including bone tissue engineering, especially in the fields of dentistry and orthopedy.

Indexed as

biocompatibilityhydrogeliCVDosteoblastPLAproliferationtissue engineering

Identifiers

PMID33430187
PMCPMC7825612
OpenAlexW3119200312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.