Evidence map›Paper›PMID 33430175›Full record

ArticleMedicina (Kaunas, Lithuania)2021

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Major Impact on Lives of Both Patients and Family Members.

Esme Brittain, Nina Muirhead, Andrew Y Finlay, Jui Vyas

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05141318 (Family Reported Outcomes in the Estimation of Societal Value of Advanced Therapy Medicinal Products), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05141318 completednot on this map

Family Reported Outcomes in the Estimation of Societal Value of Advanced Therapy Medicinal Products (ATMPs)

TypeobservationalSponsorSwansea UniversityRan2021 to 2022Enrolled18ConditionsFamily Members, CancerArmsFROM-16 Questionnaire, Semi-structured two-part interview
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025
    Pooled it
  2. Validation of the FROM-16 in family members of patients receiving advanced therapy medicinal product (ATMP).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Assessing health state utilities for people with myalgic encephalomyelitis/chronic fatigue syndrome in Australia using the EQ-5D-5L, AQoL-8D and EQ-5D-5L-psychosocial instruments.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Turning a Corner in ME/CFS Research.Medicina (Kaunas, Lithuania) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Esme BrittainSchool of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
Nina MuirheadBuckinghamshire Healthcare NHS Trust, Amersham Hospital, Amersham HP7 0JD, UK.
Andrew Y FinlaySchool of Medicine, Cardiff University, Cardiff CF14 4XN, UK.ORCID 0000-0003-2143-1646
Jui VyasSchool of Medicine, Cardiff University, Cardiff CF14 4XN, UK.
Cardiff University · GBAmersham Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Quality of LifeAdolescentAdultAdult ChildrenAgedAged, 80 and overCost of IllnessEmotionsFamilyFatigue Syndrome, ChronicFemaleHumansMaleMiddle AgedParentsSocial Interactionfamily impactFROM-16ME/CFSQoLWHOQOL-BREF

Identifiers

PMID33430175
PMCPMC7825605
OpenAlexW2419301667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.