ArticleAnimals : an open access journal from MDPI2021
Immunomodulatory Effects of Dietary Phosphorus and Calcium in Two Strains of Laying Hens.
Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 24 citations in OpenAlex.
- Chromatin accessibility of the jejunum in two high-yielding laying hen strains under divergent mineral phosphorus supply during the transition to egg laying.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Breed- and age-associated variation in hematological parameters and Toll-like receptor 2 gene expression in peripheral blood mononuclear cells of commercial and purebred laying hens during the laying cycle.Veterinary world · 2026Article
- Impact of dietary myo-inositol supplements on immune cell distribution and cytokine expression in laying hens of two different strains.Poultry science · 2026Article
- Hens and roosters of two distinct lines differ in immune cell profiles.Poultry science · 2026Article
- Impact of feeding diets without mineral P supplement on the immune system of two laying hen strains.Poultry science · 2026Article
- Dose-dependent effects of locally produced microbial phytase on caecal microbiota, hepatic insulin-likeVeterinary world · 2026Article
- Impact of in ovo myo-inositol administration on immune modulation in broiler chickens.Frontiers in immunology · 2026Article
- Calcium requirements for Japanese quail in the early growth period.Poultry science · 2025Article
- Effects of a transient lack of dietary mineral phosphorus on renal gene expression and plasma metabolites in two high-yielding laying hen strains.BMC genomics · 2025Article
- Propolis does not significantly modulate immune function in an older population: A preliminary study.Heliyon · 2024Article
- Trace Minerals in Laying Hen Diets and Their Effects on Egg Quality.Biological trace element research · 2024Review
- Nutritional Support: The Use of Antioxidants in Inflammatory Bowel Disease.International journal of molecular sciences · 2024Review
- Effects of low dietary calcium and lipopolysaccharide challenges on production performance, eggshell quality, and bone metabolism of laying hens.Frontiers in physiology · 2024Article
- RNA-Seq-based discovery of genetic variants and allele-specific expression of two layer lines and broiler chicken.Evolutionary applications · 2023Article
- The active core microbiota of two high-yielding laying hen breeds fed with different levels of calcium and phosphorus.Frontiers in physiology · 2022Article
- Multi-Omics Reveals Different Strategies in the Immune and Metabolic Systems of High-Yielding Strains of Laying Hens.Frontiers in genetics · 2022Article
- Jejunal transcriptomic profiling of two layer strains throughout the entire production period.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insufficient nutrient supply can impair the immune system, which is important for animal health and welfare. Since chicken can partly hydrolyze phytate, which is the primary phosphorus storage in plant seeds, a reduction of mineral phosphorus in the diets could be an option for more sustainable egg production. Laying hens require high concentrations of calcium that might inhibit the function of endogenous enzymes for phytate hydrolyzation. The objective of this study was to characterize the impact of standard and reduced dietary phosphorus and calcium concentrations on the number and functionality of immune cells in the peripheral and gut-associated immune system in a white and brown laying hen strain. Reduced mineral phosphorus enhanced several immune parameters such as B cells in blood and IgA concentrations in bile in both strains, and peripheral monocytes and γδ T cells in cecal tonsils in brown hens. Reduced calcium levels resulted in lower numbers of T cells in blood and cecal tonsils in both strains, suggesting negative effects on adaptive immunity. Differences between the two strains were found in almost all immune parameters. Results suggest a potentially beneficial effect of reduced dietary mineral phosphorus on the immune system that is dependent on the genetic background.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.