Evidence map›Paper›PMID 33430086›Full record

ArticleNutrients2021

Protein Digests and Pure Peptides from Chia Seed Prevented Adipogenesis and Inflammation by Inhibiting PPARγ and NF-κB Pathways in 3T3L-1 Adipocytes.

Mariana Grancieri, Hércia Stampini Duarte Martino, Elvira Gonzalez de Mejia

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. A Critical Review of the Health Benefits Associated with Chia Seeds (Salvia Hispanica L.).Plant foods for human nutrition (Dordrecht, Netherlands) · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Ancient Latin-American food crops: An overview of their nutraceutical and antiobesity peptides.Food science and technology international = Ciencia y tecnologia de los alimentos internacional · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Anti-obesity peptides from food: Production, evaluation, sources, and commercialization.Comprehensive reviews in food science and food safety · 2025
    Review
  10. Article
  11. Defatted chia (Current research in food science · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Anti-inflammatory peptide therapeutics and the role of sulphur containing amino acids (cysteine and methionine) in inflammation suppression: A review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Review
  16. Sacha Inchi (Foods (Basel, Switzerland) · 2024
    Article
  17. Article
  18. Evaluation ofLife (Basel, Switzerland) · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Mariana GrancieriDepartamento de Nutrição e Saúde, Universidade Federal de Viçosa, Viçosa, MG 36570-900, Brazil.
Hércia Stampini Duarte MartinoDepartamento de Nutrição e Saúde, Universidade Federal de Viçosa, Viçosa, MG 36570-900, Brazil.ORCID 0000-0002-8565-8439
Elvira Gonzalez de MejiaDepartment of Food Science & Human Nutrition, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0001-7426-9035
Universidade Federal de Viçosa · BRUniversity of Illinois Urbana-Champaign · US

Funding

National Institute of Food and Agriculture 1014457
6 · The paper itself

Abstract

The objective was to evaluate the mechanisms of digested total proteins (DTP), albumin, glutelin, and pure peptides from chia seed (

Indexed as

3T3-L1 CellsAdipocytesAdipogenesisAlbuminsAnimalsFatty Acid SynthasesGlutensInflammationLipid MetabolismMiceMonoacylglycerol LipasesNF-kappa BPeptidesPlant ProteinsPPAR gammaRAW 264.7 CellsAlbuminsFatty Acid SynthasesGlutensMonoacylglycerol LipasesNF-kappa BPeptidesPlant ProteinsPPAR gammaSeed Storage Proteinsadipocytesbioactive peptidesdigested proteinsinflammationobesitySalvia hispanica L.

Identifiers

PMID33430086
PMCPMC7826547
OpenAlexW3118280564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.