Evidence map›Paper›PMID 33429999›Full record

ArticleInternational journal of molecular sciences2021

Structure-Activity Relationship Modeling and Experimental Validation of the Imidazolium and Pyridinium Based Ionic Liquids as Potential Antibacterials of MDR

Ivan V Semenyuta, Maria M Trush, Vasyl V Kovalishyn, Sergiy P Rogalsky, Diana M Hodyna, Pavel Karpov, Zhonghua Xia, Igor V Tetko, Larisa O Metelytsia

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ivan V SemenyutaV.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Science of Ukraine, 1 Murmanska Street, 02660 Kyiv, Ukraine.
Maria M TrushV.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Science of Ukraine, 1 Murmanska Street, 02660 Kyiv, Ukraine.
Vasyl V KovalishynV.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Science of Ukraine, 1 Murmanska Street, 02660 Kyiv, Ukraine.ORCID 0000-0002-9352-7332
Sergiy P RogalskyV.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Science of Ukraine, 1 Murmanska Street, 02660 Kyiv, Ukraine.
Diana M HodynaV.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Science of Ukraine, 1 Murmanska Street, 02660 Kyiv, Ukraine.
Pavel KarpovInstitute of Structural Biology, Helmholtz Zentrum München-German Research Center for Environmental Health (GmbH), Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany.ORCID 0000-0003-4786-9806
Zhonghua XiaInstitute of Structural Biology, Helmholtz Zentrum München-German Research Center for Environmental Health (GmbH), Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany.ORCID 0000-0002-4219-374X
Igor V TetkoInstitute of Structural Biology, Helmholtz Zentrum München-German Research Center for Environmental Health (GmbH), Ingolstädter Landstraße 1, D-85764 Neuherberg, Germany.ORCID 0000-0002-6855-0012
Larisa O MetelytsiaV.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Science of Ukraine, 1 Murmanska Street, 02660 Kyiv, Ukraine.

Funding

Bundesministerium für Bildung, Wissenschaft und Forschung BMBF-DLR 01DK20018China Scholarship Council 201706880010
6 · The paper itself

Abstract

Online Chemical Modeling Environment (OCHEM) was used for QSAR analysis of a set of ionic liquids (ILs) tested against multi-drug resistant (MDR) clinical isolate

Indexed as

Acinetobacter baumanniiBacterial InfectionsDrug Resistance, MultipleHumansImidazolesIonic LiquidsPyridinesStaphylococcus aureusStructure-Activity RelationshipimidazoleImidazolesIonic LiquidsPyridinesAcinetobacter baumanniienoyl-ACP reductaseFabIguanidiniumimidazoliumionic liquids (ILs)OCHEMpyridiniumQSARStaphylococcus aureusStructure-Activity modeling

Identifiers

PMID33429999
PMCPMC7827895

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.