Evidence map›Paper›PMID 33429959›Full record

ArticleBrain sciences2021

Sleep-Related Declarative Memory Consolidation in Children and Adolescents with Developmental Dyslexia.

Flaminia Reda, Maurizio Gorgoni, Aurora D'Atri, Serena Scarpelli, Matteo Carpi, Erica Di Cola, Deny Menghini, Stefano Vicari, Giacomo Stella, Luigi De Gennaro

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Analytical amplitude/phase markers for neurological sleep apnea events.Neurobiology of sleep and circadian rhythms · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Flaminia RedaDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.
Maurizio GorgoniDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-5544-5483
Aurora D'AtriDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Serena ScarpelliIRCCS Fondazione Santa Lucia, 00179 Rome, Italy.ORCID 0000-0002-9260-7111
Matteo CarpiDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.
Erica Di ColaDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.
Deny MenghiniChild and Adolescent Psychiatry Unit, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0002-8418-9570
Stefano VicariChild and Adolescent Psychiatry Unit, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Giacomo StellaDepartment of Education and Human Sciences, University of Modena and Reggio Emilia, 42121 Reggio Emilia, Italy.
Luigi De GennaroDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-3613-6631
Sapienza University of Rome · ITFondazione Santa Lucia · ITBambino Gesù Children's Hospital · ITUniversità Cattolica del Sacro Cuore · ITUniversity of L'Aquila · ITUniversity of Modena and Reggio Emilia · IT

Funding

Sapienza Università di Roma AR11715C54F9A316Università Degli Studi di Modena e Reggio Emila CUP86J17000340005
6 · The paper itself

Abstract

Sleep has a crucial role in memory processes, and maturational changes in sleep electrophysiology are involved in cognitive development. Albeit both sleep and memory alterations have been observed in Developmental Dyslexia (DD), their relation in this population has been scarcely investigated, particularly concerning topographical aspects. The study aimed to compare sleep topography and associated sleep-related declarative memory consolidation in participants with DD and normal readers (NR). Eleven participants with DD and 18 NR (9-14 years old) underwent a whole-night polysomnography. They were administered a word pair task before and after sleep to assess for declarative memory consolidation. Memory performance and sleep features (macro and microstructural) were compared between the groups, and the intercorrelations between consolidation rate and sleep measures were assessed. DD showed a deeper worsening in memory after sleep compared to NR and reduced slow spindles in occipito-parietal and left fronto-central areas. Our results suggest specific alterations in local sleep EEG (i.e., sleep spindles) and in sleep-dependent memory consolidation processes in DD. We highlight the importance of a topographical approach, which might shed light on potential alteration in regional cortical oscillation dynamics in DD. The latter might represent a target for therapeutic interventions aimed at enhancing cognitive functioning in DD.

Indexed as

developmental dyslexiaEEG topographylearning disabilitiesmemory consolidationneurodevelopmental disordersNon-Rapid Eye Movement (NREM) sleeppredictive neurocognitive factorssleep oscillationssleep spindlesSlow Wave Activity

Identifiers

PMID33429959
PMCPMC7826880
OpenAlexW3120352806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.