Evidence map›Paper›PMID 33429902›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Long-Term Use of Tedizolid in Osteoarticular Infections: Benefits among Oxazolidinone Drugs.

Eva Benavent, Laura Morata, Francesc Escrihuela-Vidal, Esteban Alberto Reynaga, Laura Soldevila, Laia Albiach, Maria Luisa Pedro-Botet, Ariadna Padullés, Alex Soriano, Oscar Murillo

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Oxazolidinone antibiotics impairAntimicrobial agents and chemotherapy · 2024
    Article
  4. Review
  5. The Role of Novel Antibiotics in the Management of Diabetic Foot Infection.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Tedizolid: new data and experiences for clinical practice.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Eva BenaventInfectious Diseases Department, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, University of Barcelona, 08907 Barcelona, Spain.ORCID 0000-0001-9891-1766
Laura MorataBone and Joint Infection Study Group of the Spanish Society of Infectious Diseases and Clinical Microbiology (GEIO-SEIMC), 28003 Madrid, Spain.
Francesc Escrihuela-VidalInfectious Diseases Department, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, University of Barcelona, 08907 Barcelona, Spain.
Esteban Alberto ReynagaDepartment of Infectious Diseases, Hospital Germans Trias i Pujol, 08916 Barcelona, Spain.ORCID 0000-0002-4069-6087
Laura SoldevilaInfectious Diseases Department, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, University of Barcelona, 08907 Barcelona, Spain.
Laia AlbiachInfectious Diseases Department, Hospital Clínic-IDIBAPS, University of Barcelona, 08036 Barcelona, Spain.
Maria Luisa Pedro-BotetDepartment of Infectious Diseases, Hospital Germans Trias i Pujol, 08916 Barcelona, Spain.
Ariadna PadullésDepartment of Pharmacy, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, University of Barcelona, 08907 Barcelona, Spain.
Alex SorianoBone and Joint Infection Study Group of the Spanish Society of Infectious Diseases and Clinical Microbiology (GEIO-SEIMC), 28003 Madrid, Spain.ORCID 0000-0002-9374-0811
Oscar MurilloInfectious Diseases Department, Hospital Universitari de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, University of Barcelona, 08907 Barcelona, Spain.
Bellvitge University Hospital · ESInstituto de Salud Carlos III · ESHospital Universitari Germans Trias i Pujol · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ES

Funding

Instituto de Salud Carlos III FI16/00397
6 · The paper itself

Abstract

backgroundTo evaluate the efficacy and safety of long-term use of tedizolid in osteoarticular infections.

methodsMulticentric retrospective study (January 2017-March 2019) of osteoarticular infection cases treated with tedizolid. Failure: clinical worsening despite antibiotic treatment or the need of suppressive treatment.

resultsCases (

conclusionsLong-term use of tedizolid was effective, showing a better safety profile with less myelotoxicity and lower drug-drug interaction than linezolid. Confirmation of these advantages could make tedizolid the oxazolidinone of choice for most of osteoarticular infections.

Indexed as

diabetic foot infectionsdrug-drug interactionosteoarticular infectionsoxazolidinonestedizolid

Identifiers

PMID33429902
PMCPMC7826593
OpenAlexW3119598592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.