Evidence map›Paper›PMID 33429876›Full record

ArticleInternational journal of molecular sciences2021

Environmentally Relevant Iron Oxide Nanoparticles Produce Limited Acute Pulmonary Effects in Rats at Realistic Exposure Levels.

Chang Guo, Ralf J M Weber, Alison Buckley, Julie Mazzolini, Sarah Robertson, Juana Maria Delgado-Saborit, Joshua Z Rappoport, James Warren, Alan Hodgson, Paul Sanderson and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Asbestos and Iron.International journal of molecular sciences · 2023
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Chang GuoCentre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Didcot, Oxfordshire OX11 0RQ, UK.ORCID 0000-0002-9662-1885
Ralf J M WeberSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
Alison BuckleyCentre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Didcot, Oxfordshire OX11 0RQ, UK.
Julie MazzoliniCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH16 4SB, UK.
Sarah RobertsonCentre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Didcot, Oxfordshire OX11 0RQ, UK.
Juana Maria Delgado-SaboritSchool of Geography, Earth and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0002-7096-9744
Joshua Z RappoportDepartment of Biology, Boston College, 140 Commonwealth Avenue, Chestnut Hill, MA 02467, USA.
James WarrenCentre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Didcot, Oxfordshire OX11 0RQ, UK.
Alan HodgsonCentre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Didcot, Oxfordshire OX11 0RQ, UK.
Paul SandersonSchool of Geography, Earth and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
James Kevin ChipmanSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
Mark R ViantSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0001-5898-4119
Rachel SmithCentre for Radiation, Chemical and Environmental Hazards, Public Health England, Harwell Campus, Didcot, Oxfordshire OX11 0RQ, UK.
Public Health England · GBUniversity of Birmingham · GBBoston College · USUniversitat Jaume I · ESUniversity of Edinburgh · GBWardell Armstrong (United Kingdom) · GB

Funding

UK's Natural Environment Research Council and Medical Research Council as part of the FABLE project (From Airborne exposures to BioLogical Effects) NE/l008314
6 · The paper itself

Abstract

Iron is typically the dominant metal in the ultrafine fraction of airborne particulate matter. Various studies have investigated the toxicity of inhaled nano-sized iron oxide particles (FeO

Indexed as

Acute Lung InjuryAerosolsAir PollutantsAnimalsCell LineHumansInflammationInhalation ExposureLungMagnetic Iron Oxide NanoparticlesParticulate MatterRatsRats, Sprague-DawleyAerosolsAir PollutantsParticulate Matterinhalationiron oxidelungnanoparticleomicsratultrafine

Identifiers

PMID33429876
PMCPMC7827273
OpenAlexW3120988444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.