ArticleInternational journal of molecular sciences2021
Endogenous Opioid Signaling in the Mouse Retina Modulates Pupillary Light Reflex.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 17 citations in OpenAlex.
- Alcohol and Opioids Modulate Excitatory Inputs to the SCN.bioRxiv : the preprint server for biology · 2026Article
- Racecadotril induced bilateral uveal effusion: a case report.BMC ophthalmology · 2025Article
- Article
- Disrupted circadian rhythms and opioid-mediated adverse effects: Bidirectional relationship and putative mechanisms.Journal of neuroendocrinology · 2025Review
- The Influence of Opioids on Pupil Initial Diameter and Pupillary Dilation Velocity in ICU Patients.Acta anaesthesiologica Scandinavica · 2025Observational
- Exploring the role of beta-endorphin in activity-based anorexia in mice.Physiological reports · 2025Article
- Dopamine enhances GABAJournal of neurophysiology · 2024Article
- Dopamine enhances GABAbioRxiv : the preprint server for biology · 2023Article
- Sensorimotor Alterations Induced by Novel Fentanyl Analogs in Mice: Possible Impact on Human Driving Performances.Current neuropharmacology · 2023Article
- Morphine pharmacokinetics and opioid transporter expression at the blood-retina barrier of male and female mice.Frontiers in pharmacology · 2023Article
- µ-Opioid Receptors Expressed by Intrinsically Photosensitive Retinal Ganglion Cells Contribute to Morphine-Induced Behavioral Sensitization.International journal of molecular sciences · 2022Article
- Endogenous opioid signaling in the retina modulates sleep/wake activity in mice.Neurobiology of sleep and circadian rhythms · 2022Article
- Morphine Accumulates in the Retina Following Chronic Systemic Administration.Pharmaceuticals (Basel, Switzerland) · 2022Article
- A retinal contribution to opioid-induced sleep disorders?Frontiers in neuroscience · 2022Review
- Special Issue ofInternational journal of molecular sciences · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Opioid peptides and their receptors are expressed in the mammalian retina; however, little is known about how they might affect visual processing. The melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs), which mediate important non-image-forming visual processes such as the pupillary light reflex (PLR), express β-endorphin-preferring, µ-opioid receptors (MORs). The objective of the present study was to elucidate if opioids, endogenous or exogenous, modulate pupillary light reflex (PLR) via MORs expressed by ipRGCs. MOR-selective agonist [D-Ala
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.