Evidence map›Paper›PMID 33429470›Full record

ArticleJournal of Korean medical science2021

Process of Obtaining Social Consensus and 3-Year Functional Outcomes of the First Hand Allotransplantation in Korea.

Sang Hyun Woo, Young Woo Kim, Ho Jun Cheon, SungHo Jang, Jun Young Do, Joon Hyuk Choi, Dong Ho Kang, Hyun Jae Nam, Myung Jae Yoo, Young Seok Lee and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sang Hyun WooW Institute for Hand & Reconstructive Microsurgery, W General Hospital, Daegu, Korea. handwoo303@gmail.com.ORCID https://orcid.org/0000-0002-6397-9135
Young Woo KimW Institute for Hand & Reconstructive Microsurgery, W General Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0001-6372-6659
Ho Jun CheonW Institute for Hand & Reconstructive Microsurgery, W General Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-0854-9319
SungHo JangDepartment of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0001-6383-5505
Jun Young DoDivision of Nephrology, Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-6360-9310
Joon Hyuk ChoiDepartment of Pathology, Yeungnam University College of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-8638-0360
Dong Ho KangW Institute for Hand & Reconstructive Microsurgery, W General Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0001-8398-6968
Hyun Jae NamW Institute for Hand & Reconstructive Microsurgery, W General Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0003-3980-8640
Myung Jae YooW Institute for Hand & Reconstructive Microsurgery, W General Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0001-5106-0968
Young Seok LeeW Institute for Hand & Reconstructive Microsurgery, W General Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-0217-2661
Jin Hee ChoiW Institute for Hand & Reconstructive Microsurgery, W General Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0003-0414-0679
Hanil General Hospital · KRYeungnam University College

Funding

Yeungnam University
6 · The paper itself

Abstract

backgroundOn February 2, 2017, the surgical team of ten board-certified hand specialists of W Hospital in Korea successfully performed the nation's first hand transplantation at Yeungnam University Medical Center (YUMC). This paper reports on the legal, financial, and cultural hurdles that were overcome to open the way for hand transplantation and its functional outcomes at 36 months after the operation.

methodsW Hospital formed a memorandum of understanding with Daegu city and YUMC to comply with government regulations regarding hand transplantation. Campaigns were initiated in the media to increase public awareness and understanding. With the city's financial and legal support and the university's medical cooperation, a surgical team performed a left distal forearm hand transplantation from a brain-dead 48-year-old man to a 35-year-old left-handed man.

resultsWith this successful allotransplantation, the Korean Act on Organ Transplantation has now been amended to include hand transplantation. Korean national health insurance has also begun covering hand transplantation. Functional outcome at 36 months after the operation showed satisfactory progress in both motor and sensory functions. The disabilities of the arm, shoulder, and hand score were 23. The final Hand Transplantation Score was 90 points. Functional brain magnetic resonance imaging shows significant cortical reorganization of the corticospinal tract, and reinnervation of intrinsic muscle is observed.

conclusionsHand transplantation at the distal forearm shows very satisfactory outcomes in functional, aesthetical, and psychological aspects. Legal and financial barriers against hand transplantation have long been the most burdensome issues. Despite this momentous success, there have been no other clinical applications of vascularized composite allotransplantation due to the limited acceptance by Korean doctors and people. Further public education campaigns for vascularized composite allotransplantation are needed to increase awareness and acceptance.

Indexed as

Hand TransplantationBrainConsensusElectromyographyForearmHumansMagnetic Resonance ImagingRepublic of KoreaTreatment OutcomeVascularized Composite AllotransplantationFunctional OutcomeHand TransplantationKoreaSocial Consensus

Identifiers

PMID33429470
PMCPMC7801147
OpenAlexW3112676524

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.