ArticlePloS one2021
Whole genome sequencing of coagulase positive staphylococci from a dog-and-owner screening survey.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Phenotypic and Genotypic Diversity of Methicillin-Resistant Staphylococci in Dermatological Pets and Their Owners.Veterinary sciences · 2026Article
- Longitudinal Epidemiology of Coagulase-Positive Staphylococcal Species Recovered from Humans, Pets, and Household Environments.Antibiotics (Basel, Switzerland) · 2026Article
- Amoxicillin Resistance: An In Vivo Study on the Effects of an Approved Formulation on Antibiotic Resistance in Broiler Chickens.Animals : an open access journal from MDPI · 2025Article
- Whole Genome Sequence Analysis of Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2025Article
- Molecular identification of antibiotic-resistant and virulentJournal of advanced veterinary and animal research · 2025Article
- Comprehensive Metagenomic Analysis of Veterinary Probiotics in Broiler Chickens.Animals : an open access journal from MDPI · 2024Article
- In Vitro Microevolution and Co-Selection Assessment of Amoxicillin and Cefotaxime Impact onAntibiotics (Basel, Switzerland) · 2024Article
- In Vitro Microevolution and Co-Selection Assessment of Florfenicol Impact onAntibiotics (Basel, Switzerland) · 2023Article
- Virulence Mechanisms of Staphylococcal Animal Pathogens.International journal of molecular sciences · 2023Review
- Fosfomycin Resistance in Bacteria Isolated from Companion Animals (Dogs and Cats).Veterinary sciences · 2023Review
- Article
- Clonal relatedness of coagulase-positive staphylococci among healthy dogs and dog-owners in Spain. Detection of multidrug-resistant-MSSA-CC398 and novel linezolid-resistant-MRSA-CC5.Frontiers in microbiology · 2023Article
- An investigation of household dogs as the source in a case of human bacteraemia caused byInfection ecology & epidemiology · 2023Article
- Prevalence and antibiotic resistance ofFrontiers in cellular and infection microbiology · 2023Article
- Antimicrobial Resistance and Molecular Epidemiology ofPathogens (Basel, Switzerland) · 2022Article
- Three-Dimensional Structure Characterization and Inhibition Study of Exfoliative Toxin D FromFrontiers in pharmacology · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus aureus and S. pseudintermedius are the two most common coagulase positive staphylococci (CPS). S. aureus is more prevalent among humans, whereas S. pseudintermedius is more commonly isolated from dogs, however, both can cause various community and hospital acquired diseases in humans.
methodsIn the current study we screened 102 dogs and 84 owners in Hungary. We tested the antibiotic susceptibility of the strains and in order to get a better picture of the clonal relationship of the strains, we used pulsed-field gel electrophoresis. In addition, three pairs of isolates with identical PFGE patterns were whole genome sequenced, MLST and spa types were established.
resultsCarriage rate of S. aureus was 23.8% in humans and 4.9% in dogs and two cases of co-carriage were found among dogs and owners. S. pseudintermedius carriage rate was 2.4% and 34.3%, respectively, with only one co-carriage. The isolates were generally rather susceptible to the tested antibiotics, but high tetracycline resistance of S. pseudintermedius strains was noted. The co-carried isolates shared almost the same resistance genes (including tet(K), bla(Z), norA, mepR, lmrS, fosB) and virulence gene pattern. Apart from the common staphylococcal enzymes and cytotoxins, we found enterotoxins and exfoliative toxins as well. The two S. aureus pairs belonged to ST45-t630, ST45-t671 and ST15-t084, ST15-t084, respectively. The co-carried S. pseudintermedius isolates shared the same housekeeping gene alleles determining a novel sequence type ST1685.
conclusionsBased on the genomic data, dog-owner co-carried strains displayed only insignificant differences therefore provided evidence for potential human-to-dog and dog-to-human transmission.
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