Evidence map›Paper›PMID 33428269›Full record

ReviewEvolution & development2021

Evolution of DELLA function and signaling in land plants.

Alexandros Phokas, Juliet C Coates

Abstract readReview
In one paragraph

Review in Evolution & development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
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  5. Article
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  7. Article
  8. Gibberellins: extending the Green Revolution.Journal of experimental botany · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. ΔiScience · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexandros PhokasSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK.ORCID 0000-0002-1353-5106
Juliet C CoatesSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/M01116X/1
6 · The paper itself

Abstract

DELLA proteins are master growth regulators that repress responses to a group of plant growth hormones called gibberellins (GAs). Manipulation of DELLA function and signaling was instrumental in the development of high-yielding crop varieties that saved millions from starvation during the "Green Revolution." Despite decades of extensive research, it is still unclear how DELLA function and signaling mechanisms evolved within the land plant lineage. Here, we review current knowledge on DELLA protein function with reference to structure, posttranslational modifications, downstream transcriptional targets, and protein-protein interactions. Furthermore, we discuss older and recent findings regarding the evolution of DELLA signaling within the land plant lineage, with an emphasis on bryophytes, and identify future avenues of research that would enable us to shed more light on the evolution of DELLA signaling. Unraveling how DELLA function and signaling mechanisms have evolved could enable us to engineer better crops in an attempt to contribute to mitigating the effects of global warming and achieving global food security.

Indexed as

EmbryophytaGibberellinsAnimalsGene Expression Regulation, PlantPlant Growth RegulatorsPlant ProteinsPlantsSignal TransductionGibberellinsPlant Growth RegulatorsPlant Proteins

Identifiers

PMID33428269
PMCPMC9285615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.