Evidence map›Paper›PMID 33428182›Full record

ArticleProbiotics and antimicrobial proteins2021

Craft Beers Fermented by Potential Probiotic Yeast or Lacticaseibacilli Strains Promote Antidepressant-Like Behavior in Swiss Webster Mice.

Larissa Cardoso Silva, Heitor de Souza Lago, Márcia Oliveira Terra Rocha, Vanessa Sales de Oliveira, Roberto Laureano-Melo, Evandro Toledo Gerhardt Stutz, Breno Pereira de Paula, José Francisco Pereira Martins, Rosa Helena Luchese, André Fioravante Guerra and 1 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Sour Beer withFoods (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Larissa Cardoso SilvaCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253, Bragança, Portugal.
Heitor de Souza LagoCentro Federal de Educação Tecnológica Celso Suckow da Fonseca (CEFET/RJ), Valença, Rio de Janeiro, 27600 000, Brazil.
Márcia Oliveira Terra RochaCentro Federal de Educação Tecnológica Celso Suckow da Fonseca (CEFET/RJ), Valença, Rio de Janeiro, 27600 000, Brazil.
Vanessa Sales de OliveiraDepartment of Food Technology, Federal Rural University of Rio de Janeiro, Seropédica, Rio de Janeiro, 23.897 970, Brazil.
Roberto Laureano-MeloCentro Universitário de Barra Mansa (UBM), Barra Mansa, Rio de Janeiro, 27330-550, Brazil.
Evandro Toledo Gerhardt StutzCentro Universitário de Barra Mansa (UBM), Barra Mansa, Rio de Janeiro, 27330-550, Brazil.
Breno Pereira de PaulaCentro Federal de Educação Tecnológica Celso Suckow da Fonseca (CEFET/RJ), Valença, Rio de Janeiro, 27600 000, Brazil.
José Francisco Pereira MartinsDepartment of Food Technology, Federal Rural University of Rio de Janeiro, Seropédica, Rio de Janeiro, 23.897 970, Brazil.
Rosa Helena LucheseDepartment of Food Technology, Federal Rural University of Rio de Janeiro, Seropédica, Rio de Janeiro, 23.897 970, Brazil.
André Fioravante GuerraCentro Federal de Educação Tecnológica Celso Suckow da Fonseca (CEFET/RJ), Valença, Rio de Janeiro, 27600 000, Brazil. andrefioravanteguerra@gmail.com.ORCID 0000-0002-7226-7236
Paula RodriguesCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253, Bragança, Portugal.
Federal Center for Technological Education Celso Suckow da Fonseca · BRUniversidade Federal Rural do Rio de Janeiro · BRCentro Universitário de Barra Mansa · BRPolytechnic Institute of Bragança · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to produce a probiotic-containing functional wheat beer (PWB) by an axenic culture system with potential probiotic Saccharomyces cerevisiae var boulardii 17 and probiotic-containing functional sour beer (PSB) by a semi-separated co-cultivation system with potential probiotic Lacticaseibacillus paracasei DTA 81 and Saccharomyces cerevisiae S-04. Additionally, results obtained from in vivo behavioral tests with Swiss Webster mice treated with PWB or PSB were provided, which is scarce in the current literature. Although the use of S. boulardii to produce beers is not a novelty, this study demonstrated that S. boulardii 17 performance on sugar wort stills not completely elucidated; therefore, further studies should be considered before using the strain in industrial-scale production. Co-culture systems with lacticaseibacilli strain and S. cerevisiae have been reported in the literature for PSB production. However, lacticaseibacilli survivability in beer can be improved by semi-separated co-cultivation systems, highlighting the importance of growing lacticaseibacilli in the wort before yeast pitching. Besides, kettle hopping must be chosen as the method for hop addition to produce PSB. The dry-hopping method may prevent iso-alpha formation in the wort; however, a tendency to sediment can drag cells at the tank bottom and negatively affect L. paracasei DTA 81 viability. Despite stress factors from the matrices and the stressful conditions encountered during GI transit, potential probiotic S. boulardii 17 and potential probiotic L. paracasei DTA 81 withstood at sufficient doses to promote antidepressant effects in the mice group treated with PWB or PSB, respectively.

Indexed as

Antidepressive AgentsLactobacillalesProbioticsSaccharomyces cerevisiaeAnimalsBeerMiceSwitzerlandAntidepressive AgentsBeneficialBreweryDysbiosisGutHostMicrobes

Identifiers

PMID33428182
OpenAlexW3119716625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.