ArticleGenes & genomics2021
Metagenomics analysis of the gut microbiome in healthy and bacterial pneumonia forest musk deer.
Article in Genes & genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 19 citations in OpenAlex.
- Article
- Intelligent Veterinary Disease Management Driven by Knowledge Graph for Conservation Breeding of Captive Forest Musk Deer.Veterinary sciences · 2026Article
- Etiological and Pathological Investigation of Bacterial Pneumonia in Forest Musk Deer (Veterinary medicine international · 2026Article
- Fecal steroids, short-chain fatty acids, and microbiota in high- versus low-yielding forest musk deer.AMB Express · 2025Article
- Fecal 16S rRNA sequencing and metabolomics reveal abnormal metabolism activity in preterm infants with different gestational ages.Frontiers in cellular and infection microbiology · 2025Article
- Insights into the Gut Microbial Diversity of Wild Siberian Musk Deer (Animals : an open access journal from MDPI · 2024Article
- Analysis on Changes and Influencing Factors of the Intestinal Microbiota of Alpine Musk Deer between the Place of Origin and Migration.Animals : an open access journal from MDPI · 2023Article
- Microbiome Responses to Fecal Microbiota Transplantation in Cats with Chronic Digestive Issues.Veterinary sciences · 2023Article
- Impact of Two Phosphorus Fertilizer Formulations on Wheat Physiology, Rhizosphere, and Rhizoplane Microbiota.International journal of molecular sciences · 2023Article
- Article
- Environmental factors and gut microbiota: Toward better conservation of deer species.Frontiers in microbiology · 2023Review
- Using high-throughput sequencing to investigate the dietary composition of the Korean water deer (Hydropotes inermis argyropus): a spatiotemporal comparison.Scientific reports · 2022Article
- Isolation ofFrontiers in microbiology · 2022Article
- ITRAQ-based quantitative proteomics analysis of forest musk deer with pneumonia.Frontiers in veterinary science · 2022Article
- Changes in the gut microbiota of forest musk deer (Frontiers in microbiology · 2022Article
- Seasonal variations in the composition and diversity of gut microbiota in white-lipped deer (PeerJ · 2022Article
- Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe forest musk deer (FMD, Moschus berezovskii) is an threatened species in China. Bacterial pneumonia was found to seriously restrict the development of FMD captive breeding. Historical evidence has demonstrated the relationship between immune system and intestinal Lactobacillus in FMD.
objectiveWe sought to elucidate the differences in the gut microbiota of healthy and bacterial pneumonia FMD.
methodsThe bacterial pneumonia FMD was demonstrated by bacterial and pathological diagnosis, and the gut microbiome of healthy and bacterial pneumonia FMD was sequenced and analysed.
resultsThere are three pathogens (Pseudomonas aeruginosa, Streptococcus equinus and Trueperella pyogenes) isolated from the bacterial pneumonia FMD individuals. Compared with the healthy group, the abundance of Firmicutes and Proteobacteria in the pneumonia group was changed, and a high level of Proteobacteria was found in the pneumonia group. In addition, a higher abundance of Acinetobacter (p = 0.01) was observed in the population of the pneumonia group compared with the healthy group. Several potentially harmful bacteria and disease-related KEGG subsystems were only found in the gut of the bacterial pneumonia group. Analysis of KEGG revealed that many genes related to type IV secretion system, type IV pilus, lipopolysaccharide export system, HTH-type transcriptional regulator/antitoxin MqsA, and ArsR family transcriptional regulator were significantly enriched in the metagenome of the bacterial pneumonia FMD.
conclusionOur results demonstrated that the gut microbiome was significantly altered in the bacterial pneumonia group. Overall, our research improves the understanding of the potential role of the gut microbiota in the FMD bacterial pneumonia.
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