ReviewApplied microbiology and biotechnology2021
Psychrophilic enzymes: structural adaptation, pharmaceutical and industrial applications.
Review in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Genomic adaptations of novel halotolerant bacteria from extreme North Greenland.FEMS microbiology ecology · 2026Article
- Decoding the cold: integrated secretome profiling reveals extracellular adaptation mechanisms in Glaciozyma antarctica.Extremophiles : life under extreme conditions · 2026Article
- Partial purification and characterization of an extracellular cold-active protease from Flavobacterium azizsancarii, a novel Antarctic isolate.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Cold-adapted carboxylesterases from Alcanivoracaceae active with a wide range of synthetic polyesters.Applied microbiology and biotechnology · 2026Article
- Cold-adaptive variations in the membrane lipid composition in polar species of the ciliateFrontiers in microbiology · 2026Article
- Structural and functional annotation of Glaciozyma antarctica hypothetical proteins using integrated modeling pipelines.Extremophiles : life under extreme conditions · 2025Article
- Article
- Identification and characterization of a novel β-galactosidase active at low temperatures from the Antarctic fungus Tetracladium sp., expressed in Saccharomyces cerevisiae.Microbial cell factories · 2025Article
- Highly efficient degradation of polybutylene succinate (PBS) and polycaprolactone (PCL) by a recombinant marine fungal cutinase.Applied and environmental microbiology · 2025Article
- Isolation and characterization of a bacteria of Cupriavidus genus from Indian Himalayan region and its evaluation for production of Poly-3-hydroxybutyrate.Archives of microbiology · 2025Article
- Loop Dynamics Mediate Thermal Adaptation of Two Xylanases from Marine Bacteria.International journal of molecular sciences · 2025Article
- Progress and application of intelligent nanomedicine in urinary system tumors.Journal of pharmaceutical analysis · 2024Review
- Bacterial Diversity, Metabolic Profiling, and Application Potential of Antarctic Soil Metagenomes.Current issues in molecular biology · 2024Article
- Molecular Biology Applications of Psychrophilic Enzymes: Adaptations, Advantages, Expression, and Prospective.Applied biochemistry and biotechnology · 2024Review
- From freezing to functioning: cellular strategies of cold-adapted bacteria for surviving in extreme environments.Archives of microbiology · 2024Review
- A Bibliometric Analysis: Current Perspectives and Potential Trends of Enzyme Thermostability from 1991-2022.Applied biochemistry and biotechnology · 2024Article
- Biochemical and in silico structural characterization of a cold-active arginase from the psychrophilic yeast, Glaciozyma antarctica PI12.Extremophiles : life under extreme conditions · 2024Article
- Characterization of a novel cold-adapted GH1 β-glucosidase fromCurrent research in food science · 2024Article
- A general overview of the multifactorial adaptation to cold: biochemical mechanisms and strategies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Review
- Identification and genome-wide analysis provide insights into the genetic diversity and biotechnological potentials of novel cold-adapted Acinetobacter strain.Extremophiles : life under extreme conditions · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psychrophiles are cold-living microorganisms synthesizing enzymes that are permanently active at almost near-zero temperatures. Psychrozymes are supposed to be structurally more flexible than their homologous proteins. This structural flexibility enables these proteins to undergo conformational changes during catalysis and improve catalytic efficiency at low temperatures. The outstanding characteristics of the psychrophilic enzymes have attracted the attention of the scientific community to utilize them in a wide variety of industrial and pharmaceutical applications. In this review, we first highlight the current knowledge of the cold-adaptation mechanisms of the psychrophiles. In the sequel, we describe the potential applications of the enzymes in different biotechnological processes specifically, in the production of industrial and pharmaceutical products. KEY POINTS: • Methods that organisms have evolved to survive and proliferate at cold environments. • The economic benefits due to their high activity at low and moderate temperatures. • Applications of the psychrophiles in biotechnological and pharmaceutical industry.
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Registered trials
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