Evidence map›Paper›PMID 33427875›Full record

ArticleThe Journal of cell biology2021

Granular detail of β cell structures for insulin secretion.

Jonathan S Bogan

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of cell biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jonathan S BoganSection of Endocrinology and Metabolism, Department of Internal Medicine; and Department of Cell Biology, Yale School of Medicine, New Haven, CT.
Yale University · US

Funding

Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI Kevan C Herold, GERALD I SHULMAN · 1993 to 2026
$44.0M
Vesicle Translocation and the Metabolic SyndromeR01DK092661 · NIDDK · YALE UNIVERSITY · PI BOGAN, JONATHAN · 2012 to 2018
$2.0M
Vesicle Translocation and the Metabolic SyndromeR56DK092661 · NIDDK · YALE UNIVERSITY · PI BOGAN, JONATHAN · 2020 to 2020
$168k
NIDDK NIH HHS P30 DK045735NIDDK NIH HHS R01 DK092661NIDDK NIH HHS R56 DK092661
6 · The paper itself

Abstract

Pancreatic β cells secrete insulin in response to increased glucose concentrations. Müller et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202010039) use 3D FIB-SEM to study the architecture of these cells and to elucidate how glucose stimulation remodels microtubules to control insulin secretory granule exocytosis.

Indexed as

Insulin-Secreting CellsExocytosisInsulinInsulin SecretionSecretory VesiclesInsulin

Identifiers

PMID33427875
PMCPMC7802365
OpenAlexW3119315893

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.