Evidence map›Paper›PMID 33427646›Full record

ArticleeLife2021

Temporal evolution of single-cell transcriptomes of

Qijing Xie, Maria Brbic, Felix Horns, Sai Saroja Kolluru, Robert C Jones, Jiefu Li, Anay R Reddy, Anthony Xie, Sayeh Kohani, Zhuoran Li and 9 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Modern Mining: The Role of Single-cell RNA Sequencing in Advancing Neuroscience Research.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Qijing XieDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.ORCID 0000-0002-0997-8326
Maria BrbicDepartment of Computer Science, Stanford University, Stanford, United States.
Felix HornsDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0001-5872-5061
Sai Saroja KolluruDepartment of Bioengineering, Stanford University, Stanford, United States.
Robert C JonesDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0001-7235-9854
Jiefu LiDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.ORCID 0000-0002-0062-4652
Anay R ReddyDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Anthony XieDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Sayeh KohaniDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Zhuoran LiDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Colleen N McLaughlinDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Tongchao LiDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Chuanyun XuDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
David VacekDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
David J LuginbuhlDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Jure LeskovecDepartment of Computer Science, Stanford University, Stanford, United States.
Stephen R QuakeDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0002-1613-0809
Liqun LuoDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.ORCID 0000-0001-5467-9264
Hongjie LiDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, United States.
Howard Hughes Medical Institute · USStanford University · USChan Zuckerberg Initiative (United States) · US

Funding

Assembly of the Central Olfactory Networks in DrosophilaR01DC005982 · NIDCD · STANFORD UNIVERSITY · PI LIQUN LUO · 2003 to 2026
$8.1M
Characterizing the assembly and age-related decline of neural circuits in Drosophila by single-cell profilingK99AG062746 · NIA · STANFORD UNIVERSITY · PI LI, HONGJIE · 2019 to 2020
$254k
Howard Hughes Medical InstituteNIA NIH HHS K99 AG062746NIDCD NIH HHS R01 DC005982NIH HHS 1K99AG062746
6 · The paper itself

Abstract

Neurons undergo substantial morphological and functional changes during development to form precise synaptic connections and acquire specific physiological properties. What are the underlying transcriptomic bases? Here, we obtained the single-cell transcriptomes of

Indexed as

TranscriptomeAnimalsDrosophila melanogasterNeuritesOlfactory NerveSingle-Cell AnalysisTime FactorsD. melanogasterneural developmentneuroscienceolfactory circuitRNA sequencingsingle-celltranscriptomewiring

Identifiers

PMID33427646
PMCPMC7870145
OpenAlexW3119698738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.