Evidence map›Paper›PMID 33427563›Full record

ArticleTissue barriers2021

Function of Multidrug Resistance Transporters is Disrupted by Infection Mimics in Human Brain Endothelial Cells.

Guinever Eustaquio Do Imperio, Phetcharawan Lye, Enrrico Bloise, Stephen G Matthews

Open access · bronzeAbstract read
In one paragraph

Article in Tissue barriers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
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  9. Fetal glucocorticoid exposure leads to sex-specific changes in drug-transporter function at the blood-brain barrier in juvenile guinea pigs.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Guinever Eustaquio Do ImperioSinai Health System, Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada.
Phetcharawan LyeSinai Health System, Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada.
Enrrico BloiseSinai Health System, Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada.
Stephen G MatthewsSinai Health System, Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada.
Sinai Health System · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

P-glycoprotein (

Indexed as

Biological TransportBrainDrug Resistance, MultipleEndothelial CellsGene ExpressionHumansblood-brain barrier (BBB)breast Cancer Resistance Protein (BCRP/ABCG2)cytokineshCMEC/D3Infection mimicslpsp-glycoprotein (P-gp/ABCB1)polyi:CssRNA

Identifiers

PMID33427563
PMCPMC8078541
OpenAlexW3120660728

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.