ArticleMagnetic resonance in medicine2021
Optimization of adiabatic pulses for pulsed arterial spin labeling at 7 tesla: Comparison with pseudo-continuous arterial spin labeling.
Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Dynamic BMagnetic resonance in medicine · 2025Article
- Article
- Whole-Cerebrum distortion-free three-dimensional pseudo-continuous arterial spin labeling at 7T.NeuroImage · 2023Article
- Whole-Cerebrum distortion-free three-dimensional pseudo-Continuous Arterial Spin Labeling at 7T.medRxiv : the preprint server for health sciences · 2023Article
- Recent Technical Developments in ASL: A Review of the State of the Art.Magnetic resonance in medicine · 2022Review
- Advanced design of MRI inversion pulses for inhomogeneous field conditions by optimal control.NMR in biomedicine · 2022Article
- Optimization of pseudo-continuous arterial spin labeling at 7T with parallel transmission B1 shimming.Magnetic resonance in medicine · 2022Article
- High-Resolution Neurovascular Imaging at 7T: Arterial Spin Labeling Perfusion, 4-Dimensional MR Angiography, and Black Blood MR Imaging.Magnetic resonance imaging clinics of North America · 2021Review
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Authors and funding
6 authors.
Funding
Abstract
purposeTo optimize and evaluate adiabatic pulses for pulsed arterial spin labeling at ultrahigh field 7 tesla.
methodsFour common adiabatic inversion pulses, including hyperbolic secant, wideband uniform rate smooth truncation, frequency offset corrected inversion, and time-resampled frequency offset corrected inversion pulses, were optimized based on a custom-defined loss function that included labeling efficiency and inversion band uniformity. The optimized pulses were implemented in flow-sensitive alternating inversion recovery sequences and tested on phantom and 11 healthy volunteers with 2 constraints: 1) specific absorption rate normalized; and 2) equal peak RF amplitude, respectively. A pseudo-continuous arterial spin labeling sequence was implemented for comparison. Quantitative metrics such as perfusion and relative labeling efficiency versus residual tissue signal were calculated.
resultsAmong the 4 pulses, the wideband uniform rate smooth truncation pulse yielded the lowest loss in simulation and achieved a good balance between labeling efficiency and residual tissue signal from both phantom and in vivo experiments. Wideband uniform rate smooth truncation-pulsed arterial spin labeling showed significantly higher relative labeling efficiency compared to the other sequences (P < .01), whereas the perfusion signal was increased by 40% when the highest
conclusionOptimized wideband uniform rate smooth truncation pulse with the highest
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