ArticleThe Australian & New Zealand journal of obstetrics & gynaecology2021
Topical treatment of vulvodynia, dyspareunia and pudendal neuralgia: A single clinic audit of amitriptyline and oestriol in organogel.
Article in The Australian & New Zealand journal of obstetrics & gynaecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Effectiveness and Tolerability of Topical Amitriptyline 10% Plus Lidocaine 2% Gel in Adults With Post-Traumatic Trigeminal Neuropathic Pain: A Real-World Evidence Study.Journal of oral rehabilitation · 2026Observational
- Topical analgesics for neuropathic pain: an evidence-informed guide for the practicing clinician.Pain medicine (Malden, Mass.) · 2026Review
- The Diagnosis and Management of Pudendal Neuralgia.Pain and therapy · 2026Review
- Understanding Patient Experiences of Vulvodynia Through Reddit: Qualitative Analysis.JMIR infodemiology · 2025Article
- Pudendal Neuralgia: A Review of the Current Literature.Current pain and headache reports · 2025Review
- Effectiveness of topical gabapentin in the treatment of vulvodynia: a narrative synthesis.Frontiers in pain research (Lausanne, Switzerland) · 2023Review
- A scoping review of vulvodynia research: Diagnosis, treatment, and care experiences.Women's health (London, England)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVulvodynia and pudendal neuralgia comprise significant contributors to vulvar-related pain and its impact on daily life.
aimA retrospective clinical audit was conducted at the Women's Health & Research Institute of Australia, Sydney, to determine the pattern of use and the efficacy of the application of topical amitriptyline 0.5% plus oestriol 0.03% in organogel (AOO), to the vulvar vestibule in reducing the impact of pain on daily life. MATERIALS AND
methodsThere were 1174 patients who received a script from May 2017 until February 2020: 1054 patients agreed to be contacted and had a valid email address.
resultsThere were 376 (35.7%) patients who replied. Pain with intercourse was the main indication for use. Treatment was rated effective by 51.2% (95% CI: 35.4-66.8%) of patients less than 30 years of age, 66.7% (95% CI: 57.3-74.9%) of patients 30-50 years of age, and 58.3% (95% CI: 50.9-65.4%) in patients over 50. Stinging at the site of application was the most commonly reported side effect.
conclusionTopical AOO is an effective and well-tolerated treatment for vulvar pain.
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Registered trials
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