Evidence map›Paper›PMID 33427200›Full record

ArticleeLife2021

Selfing is the safest sex for

Luke M Noble, John Yuen, Lewis Stevens, Nicolas Moya, Riaad Persaud, Marc Moscatelli, Jacqueline L Jackson, Gaotian Zhang, Rojin Chitrakar, L Ryan Baugh and 4 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
4.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 71 citations in OpenAlex.

  1. T2T genomes ofGenome research · 2026
    Article
  2. DivergenteLife · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. A Male Expressed Copulatory Plug Increases Female Fertility inbioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. bioRxiv : the preprint server for biology · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. A gap-free, telomere-to-telomere genome assembly for thebioRxiv : the preprint server for biology · 2026
    Article
  13. Global genomic diversity of the selfing nematodebioRxiv : the preprint server for biology · 2026
    Article
  14. Article
  15. Article
  16. High-Throughput Toxicity Screening withEnvironmental science & technology · 2026
    Review
  17. bioRxiv : the preprint server for biology · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Luke M NobleDepartment of Biology and Center for Genomics & Systems Biology, New York University, New York, United States.ORCID 0000-0002-5161-4059
John YuenDepartment of Biology and Center for Genomics & Systems Biology, New York University, New York, United States.ORCID 0000-0002-1569-3298
Lewis StevensDepartment of Molecular Biosciences, Northwestern University, Evanston, United States.ORCID 0000-0002-6075-8273
Nicolas MoyaDepartment of Molecular Biosciences, Northwestern University, Evanston, United States.ORCID 0000-0002-6817-1784
Riaad PersaudDepartment of Biology and Center for Genomics & Systems Biology, New York University, New York, United States.
Marc MoscatelliDepartment of Biology and Center for Genomics & Systems Biology, New York University, New York, United States.
Jacqueline L JacksonDepartment of Biology and Center for Genomics & Systems Biology, New York University, New York, United States.ORCID 0000-0001-5376-0968
Gaotian ZhangDepartment of Molecular Biosciences, Northwestern University, Evanston, United States.
Rojin ChitrakarDepartment of Biology, Duke University, Durham, United States.
L Ryan BaughDepartment of Biology, Duke University, Durham, United States.ORCID 0000-0003-2148-5492
Christian BraendleInstitut de Biologie Valrose, Université Côte d'Azur, CNRS, Inserm, Nice, France.
Erik C AndersenDepartment of Molecular Biosciences, Northwestern University, Evanston, United States.ORCID 0000-0003-0229-9651
Hannah S SeidelDepartment of Biology, Eastern Michigan University, Ypsilanti, United States.
Matthew V RockmanDepartment of Biology and Center for Genomics & Systems Biology, New York University, New York, United States.ORCID 0000-0001-6492-8906
New York University · USNorthwestern University · USCentre National de la Recherche Scientifique · FRDuke University · USEastern Michigan University · US

Funding

Discovery of conserved molecular mechanisms underlying population-wide variation in toxin responsesR01ES029930 · NIEHS · NORTHWESTERN UNIVERSITY · PI ANDERSEN, ERIK CHRISTIAN, BAUGH, LARRY RYAN · 2019 to 2023
$3.2M
Discovery and Characterization of Quantitative Trait NucleotidesR01GM089972 · NIGMS · NEW YORK UNIVERSITY · PI ROCKMAN, MATTHEW · 2009 to 2013
$1.5M
Genetic analysis of segregating recessive variationR01GM121828 · NIGMS · NEW YORK UNIVERSITY · PI ROCKMAN, MATTHEW · 2017 to 2020
$1.5M
NIEHS NIH HHS ES029930NIEHS NIH HHS R01 ES029930NIGMS NIH HHS GM089972NIGMS NIH HHS GM121828NIGMS NIH HHS R01 GM089972NIGMS NIH HHS R01 GM121828
6 · The paper itself

Abstract

Mating systems have profound effects on genetic diversity and compatibility. The convergent evolution of self-fertilization in three

Indexed as

Biological EvolutionSelf-FertilizationAnimalsCaenorhabditisbalancing selectioncaenorhabditis tropicalisC. elegansevolutionary biologygene drivegeneticsgenomicsmating systemspopulation geneticsselfing

Identifiers

PMID33427200
PMCPMC7853720
OpenAlexW3118568829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.