ArticleDevelopment and psychopathology2020
Sensitive periods for psychosocial risk in childhood and adolescence and cardiometabolic outcomes in young adulthood.
Article in Development and psychopathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Sensitive periods to social adversity in immune and metabolic development: A systematic review.Psychoneuroendocrinology · 2025Pooled it
- Early-life adversity before age 5 is associated with reduced cardiometabolic health characterized by increased arterial stiffness and inflammation in adolescence.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Childhood cumulative risk and relationship addiction: a developmental timing-pathway differentiation-node buffering integrative model.Frontiers in psychology · 2026Article
- Life Course Financial Hardship and Fecundability in a North American Preconception Cohort Study.Epidemiology (Cambridge, Mass.) · 2025Article
- Positive childhood experiences and adult cardiovascular health.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Article
- Eating behaviors as pathways from early childhood adversity to adolescent cardiometabolic risk.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Article
- Infant effortful control predicts BMI trajectories from infancy to adolescence.Pediatric obesity · 2023Article
- Is only-child status associated with a higher blood pressure in adolescence? An observational study.European journal of pediatrics · 2023Observational
- From childhood obesity risk to healthy growth in the U.S.: A 10-year social work research & policy update.Preventive medicine reports · 2023Article
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- The mediating pathways between parental separation in childhood and offspring hypertension at midlife.Scientific reports · 2022Article
- Preconception stress exposure from childhood to adolescence and birth outcomes: The impact of stress type, severity and consistency.Frontiers in reproductive health · 2022Article
- Sex-Specific Associations Between Early-Life Unpredictability and Trajectories of Body Mass Index From Infancy to Adolescence.Biopsychosocial science and medicineArticle
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
Greater psychosocial risk in childhood and adolescence predicts poorer cardiometabolic outcomes in adulthood. We assessed whether the timing of psychosocial risk from infancy through adolescence predicts cardiometabolic outcomes in young adulthood. Young adults and their mothers participated in a longitudinal study beginning in infancy in Santiago, Chile (N = 1040). At infancy, 5 years, 10 years, and adolescence, mothers reported on depressive symptoms, stressful experiences, support for child development in the home, father absence, parental education, and socioeconomic status (SES) to create a psychosocial risk composite at each time point. Young adults (52.1% female; 21-27 years) provided fasting serum samples and participated in anthropometric and blood pressure (BP) assessments, including a dual-energy X-ray absorptiometry (DXA) scan for measuring body fat. Greater infant psychosocial risk was associated with a greater young adult metabolic syndrome score (β = 0.07, 95% confidence intervals (CI): 0.01 to 0.13, p = 0.02), a higher body mass index and waist circumference composite (β = 0.08, 95% CI: 0.03 to 0.13, p = 0.002), and a higher body fat (DXA) composite (β = 0.07, 95% CI: 0.01 to 0.12, p = 0.02). No psychosocial risk measure from any time point was associated with BP. Infant psychosocial risk predicted cardiometabolic outcomes in young adulthood better than psychosocial risk at 5 years, 10 years, or adolescence, mean of psychosocial risk from infancy through adolescence, and maximum of psychosocial risk at any one time. Consistent with the Developmental Origins of Health and Disease model, findings suggest that infancy is a sensitive period for psychosocial risk leading to poorer cardiometabolic outcomes in young adulthood.
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