Evidence map›Paper›PMID 33427182›Full record

ArticleDevelopment and psychopathology2020

Cortisol and socioeconomic status in early childhood: A multidimensional assessment.

Amanda R Tarullo, Charu T Tuladhar, Katie Kao, Eleanor B Drury, Jerrold Meyer

Abstract read
In one paragraph

Article in Development and psychopathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amanda R TarulloDepartment of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
Charu T TuladharDepartment of Psychological and Brain Sciences, Boston University, Boston, MA, USA.
Katie KaoHarvard Medical School, Brazelton Touchpoints Center, Division of Developmental Medicine, Boston Children's Hospital,Boston, MA, USA.
Eleanor B DruryDepartment of Psychology, University of Bath, Bath, UK.
Jerrold MeyerDepartment of Psychological and Brain Sciences, University of Massachusetts, Amherst, MA, USA.

Funding

Hair Cortisol as a Biomarker of Chronic Early Life StressR03HD082550 · NICHD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI TARULLO, AMANDA · 2015 to 2016
$177k
NICHD NIH HHS R03 HD082550
6 · The paper itself

Abstract

The hypothalamic-pituitary-adrenal (HPA) axis is sensitive to early life stress, with enduring consequences for biological stress vulnerability and health (Gunnar & Talge, 2008). Low socioeconomic status (SES) is associated with dysregulation of the stress hormone cortisol in early childhood. However, a mechanistic understanding of this association is lacking. Multidimensional assessment of both SES and cortisol is needed to characterize the intricate relations between SES and cortisol function in early childhood. We assessed parent-reported family income, parent education, occupational prestige, neighborhood risk, food insecurity, and household chaos for 12-month-old infants (N = 90) and 3.5-year-old children (N = 91). Hair cortisol concentration (HCC) was obtained from parent and child, indexing chronic biological stress, and diurnal salivary cortisol was measured in the children. Controlling for parent HCC, parent education uniquely predicted infant and child HCC and, in addition, neighborhood risk uniquely predicted infant HCC. Household chaos predicted bedtime salivary cortisol concentration (SCC) for both infants and children, and infant daily cortisol output. Food insecurity was associated with flattened cortisol slope in 3.5-year-old children. Parental sensitivity did not mediate relations between SES and cortisol. Results highlight the utility of SES measures that index unpredictable and unsafe contexts, such as neighborhood risk, food insecurity, and household chaos.

Indexed as

HydrocortisoneSalivaChildChild, PreschoolHumansHypothalamo-Hypophyseal SystemInfantPituitary-Adrenal SystemSocial ClassStress, PsychologicalHydrocortisonefood insecurityhair cortisolsalivary cortisolsocioeconomic statusstress

Identifiers

PMID33427182
PMCPMC7938639

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.