Evidence map›Paper›PMID 33427054›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2021

Investigating the complex interplay between genotype and high-fat-diet feeding in the lactating mammary gland using the

Adrienne A Cheng, Wenli Li, Teresa M Walker, Caylee Silvers, Lisa M Arendt, Laura L Hernandez

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Adrienne A ChengDepartment of Nutritional Sciences, University of Wisconsin, Madison, Wisconsin.
Wenli LiUS Department of Agriculture-Dairy Forage, Madison, Wisconsin.
Teresa M WalkerDepartment of Animal and Dairy Sciences, University of Wisconsin, Madison, Wisconsin.
Caylee SilversDepartment of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin.
Lisa M ArendtDepartment of Comparative Biosciences, University of Wisconsin, Madison, Wisconsin.
Laura L HernandezDepartment of Animal and Dairy Sciences, University of Wisconsin, Madison, Wisconsin.ORCID 0000-0001-7591-5203
University of Wisconsin–Madison · USU.S. Dairy Forage Research Center · US

Funding

PQ2 Obesity-induced fibrocytes promote breast cancer progressionR01CA227542 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI ARENDT, LISA M · 2018 to 2022
$1.7M
NCI NIH HHS R01 CA227542NIH/NCI CA227542U.S. Department of Agriculture (USDA) 5090-31000-026-00-DU.S. Department of Agriculture (USDA) MSN158160UW Madison Graduate School MSN215653
6 · The paper itself

Abstract

Obesity is a prevailing problem across the globe. Women who are obese have difficulty initiating and sustaining lactation. However, the impact of genetics and diet on breastfeeding outcomes is understudied. Here we explore the effect of diet and genotype on lactation. We utilized the low-density lipoprotein receptor (

Indexed as

Diet, High-FatLactationAnimalsDietary FatsFemaleGene-Environment InteractionGenotypeMammary Glands, AnimalMaternal Nutritional Physiological PhenomenaMiceMice, KnockoutMice, ObeseObesityReceptors, LDLTryptophan HydroxylaseDietary FatsReceptors, LDLTph1 protein, mouseTryptophan Hydroxylasehigh-fat dietlactationmammary glandobesityserotonin

Identifiers

PMID33427054
PMCPMC7988787
OpenAlexW3118891726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.