Evidence map›Paper›PMID 33427049›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2021

Congenital ablation of

Encarnacion Torres, Inmaculada Velasco, Delphine Franssen, Violeta Heras, Francisco Gaytan, Silvia Leon, Victor M Navarro, Rafael Pineda, M Luz Candenas, Antonio Romero-Ruiz and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Encarnacion TorresDepartment of Cell Biology, Physiology and Immunology, Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.
Inmaculada VelascoDepartment of Cell Biology, Physiology and Immunology, Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.
Delphine FranssenDepartment of Cell Biology, Physiology and Immunology, Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.
Violeta HerasDepartment of Cell Biology, Physiology and Immunology, Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.
Francisco GaytanDepartment of Cell Biology, Physiology and Immunology, Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.
Silvia LeonDepartment of Cell Biology, Physiology and Immunology, Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.
Victor M NavarroDivision of Endocrinology, Department of Medicine, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Rafael PinedaDepartment of Cell Biology, Physiology and Immunology, Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.
M Luz CandenasInstituto de Investigaciones Químicas, CSIC, Seville, Spain.
Antonio Romero-RuizDepartment of Cell Biology, Physiology and Immunology, Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.
Manuel Tena-SempereDepartment of Cell Biology, Physiology and Immunology, Instituto Maimonides de Investigación Biomédica de Córdoba (IMIBIC), University of Córdoba, Córdoba, Spain.ORCID 0000-0002-4741-5567
Instituto de Salud Carlos III · ESBrigham and Women's Hospital · USInstituto de Investigaciones Químicas · ESUniversity of Turku · FI

Funding

Characterization of the role of the amygdala in reproductive functionR01HD099084 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI NAVARRO, VICTOR MANUEL · 2020 to 2024
$2.3M
Dissecting the Role of Tachykinins in the Generation of GnRH PulsesR01HD090151 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI NAVARRO, VICTOR MANUEL · 2017 to 2021
$1.7M
NICHD NIH HHS R01 HD090151NICHD NIH HHS R01 HD099084
6 · The paper itself

Abstract

Tachykinin (TAC) signaling is an important element in the central control of reproduction. TAC family is mainly composed of substance P (SP), neurokinin A (NKA), and NKB, which bind preferentially to NK1, NK2, and NK3 receptors, respectively. While most studies have focused on the reproductive functions of NKB/NK3R, and to a lesser extent SP/NK1R, the relevance of NK2R, encoded by

Indexed as

AnimalsFemaleGonadal Steroid HormonesHypothalamusLuteinizing HormoneMaleMiceMice, KnockoutMice, ObesePregnancyPrenatal Exposure Delayed EffectsReceptors, Neurokinin-2ReproductionSignal TransductionTranscriptomeGonadal Steroid HormonesLuteinizing HormoneReceptors, Neurokinin-2gonadotropinsneuroendocrinologyneurokinin Atachykinin receptorstachykinins

Identifiers

PMID33427049
PMCPMC8828271
OpenAlexW3119486601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.