ArticleVisual computing for industry, biomedicine, and art2021
High-speed high-resolution laser diode-based photoacoustic microscopy for in vivo microvasculature imaging.
Article in Visual computing for industry, biomedicine, and art, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Advanced methods of wearable ultrasound and photoacoustic imaging devices: A review.Photoacoustics · 2026Article
- A comprehensive review of high-performance photoacoustic microscopy systems.Photoacoustics · 2025Review
- Towards affordable biomedical imaging: Recent advances in low-cost, high-resolution optoacoustic microscopy.Journal of microscopy · 2025Review
- Multi-parametric Photoacoustic Imaging Combined with Acoustic Radiation Force Impulse Imaging for Applications in Tissue Engineering.Annals of biomedical engineering · 2025Article
- Impact of skin tone on target size detectability in photoacoustic breast imaging.Biophotonics discovery · 2024Article
- Review of low-cost light sources and miniaturized designs in photoacoustic microscopy.Journal of biomedical optics · 2024Review
- Super-Low-Dose Functional and Molecular Photoacoustic Microscopy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Low-cost high-resolution photoacoustic microscopy of blood oxygenation with two laser diodes.Biomedical optics express · 2022Article
- High-resolution photoacoustic microscopy with deep penetration through learning.Photoacoustics · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Laser diodes (LDs) have been considered as cost-effective and compact excitation sources to overcome the requirement of costly and bulky pulsed laser sources that are commonly used in photoacoustic microscopy (PAM). However, the spatial resolution and/or imaging speed of previously reported LD-based PAM systems have not been optimized simultaneously. In this paper, we developed a high-speed and high-resolution LD-based PAM system using a continuous wave LD, operating at a pulsed mode, with a repetition rate of 30 kHz, as an excitation source. A hybrid scanning mechanism that synchronizes a one-dimensional galvanometer mirror and a two-dimensional motorized stage is applied to achieve a fast imaging capability without signal averaging due to the high signal-to-noise ratio. By optimizing the optical system, a high lateral resolution of 4.8 μm has been achieved. In vivo microvasculature imaging of a mouse ear has been demonstrated to show the high performance of our LD-based PAM system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.