ReviewImmunogenetics2021
The intersection of stress, sex and immunity in fishes.
Review in Immunogenetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 73 citations in OpenAlex.
- Sex-Stratified Gut Microbiota Dysbiosis in Cultured Big-Belly Seahorses During a Mass Mortality Outbreak.Current issues in molecular biology · 2026Article
- Zoonotic nematode larvae in Greenland halibut (International journal for parasitology. Parasites and wildlife · 2026Article
- Developmental and tissue-specific expression of thyrotropin-releasing hormone signaling genes in zebrafish and its association with glycemic regulation.Biology open · 2026Article
- Potential Physiological and Molecular Mechanisms Underlying Low Viability of Gynogenetic WW-Type Super-Female Sterlet (International journal of molecular sciences · 2025Article
- Stress in the spotlight: impacts of stress on learning and memory in a cichlid fish.Animal cognition · 2025Article
- ZW and XY Sex Chromosomes Drive Rapid and Distinctive Evolution of Sex-Biased Gene Expression.Molecular ecology · 2025Article
- Screening a new European hake (Merluccius merluccius) chromosome-level genome assembly suggests an XX/XY sex-determining system driven by the SRY-box transcription factor 3 (sox3).G3 (Bethesda, Md.) · 2025Article
- The ability of dietary essential oils to mitigate nickel-induced growth retardation, immune-antioxidant suppression, and endoplasmic reticulum stress activation in Nile tilapia.Fish physiology and biochemistry · 2025Article
- Ameliorative potential of Populus alba leaf powder against hexaflumuron exposure in Nile tilapia: immune-antioxidant, biochemical, histological, and transcriptomic analysis.Fish physiology and biochemistry · 2025Article
- Transcriptomic Analysis Provides New Insights into Oocyte Growth and Maturation in Greater Amberjack (Animals : an open access journal from MDPI · 2025Article
- Sexual dimorphism in the DNA methylation pattern after immune stimulation in the zebrafish (Frontiers in cell and developmental biology · 2025Article
- The Effect of Stress on the Skin Welfare of Lumpfish (Animals : an open access journal from MDPI · 2024Article
- Early stress exposure on zebrafish development: effects on survival, malformations and molecular alterations.Fish physiology and biochemistry · 2024Article
- Novel insights on microbiome dynamics during a gill disease outbreak in farmed rainbow trout (Oncorhynchus mykiss).Scientific reports · 2024Article
- Gender-specific responses in gene expression of Nile tilapia (Oreochromis niloticus) to heavy metal pollution in different aquatic habitats.Scientific reports · 2024Article
- Navigating sex and sex roles: deciphering sex-biased gene expression in a species with sex-role reversal (Royal Society open science · 2024Article
- Etiology of Ulcerative Dermal Necrosis (UDN) in Brown Trout (Pathogens (Basel, Switzerland) · 2024Article
- Are fish immunocompetent enough to face climate change?Biology letters · 2024Review
- Capture and discard practises associated with an ornamental fishery affect the metabolic rate and aerobic capacity of three-striped dwarf cichlidsConservation physiology · 2024Article
- Molecular Analysis and Sex-specific Response of the Hepcidin Gene in Yellow Perch (Perca Flavescens) Following Lipopolysaccharide Challenge.Probiotics and antimicrobial proteins · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While sexual dimorphism in immune responses has been documented in other vertebrates, evidence for a similar phenomenon in fish is lacking. Here, we review the relationship between immunity, stress, spawning, and sex hormones in fish to gain a better understanding of sex-based differences in fish immune responses and its consequences for aquaculture. It is well known that there is a strong link between the stress response and immune function in fish. In addition, research to date has demonstrated that sexual dimorphism in the stress response exists in many species; yet, the relationship between the sexual dimorphic stress responses and immune function has rarely been explored together. Aside from stress, spawning is also known to trigger changes in fish immune responses. Estrogens and androgens have been shown to modulate the immune system which could account for differences between the two sexes of fish when spawning; however, evidence regarding the sexual dimorphism of these changes varies between fishes and is likely related to the spawning strategy employed by a given species. Sex hormones are also used in aquaculture practices to produce monosex populations, and exposure to these hormones early in development has been shown to impact the development of immune organs in several fishes. While female fish are generally thought to be more robust than males, aquaculture practices should also consider the role that maternal stress has on the immune function of the offspring and what role this plays in compromising the immune response of farmed fish.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.