Evidence map›Paper›PMID 33426378›Full record

ArticleJACC. Basic to translational science2020

Phosphorylcholine Antibodies Preserve Cardiac Function and Reduce Infarct Size by Attenuating the Post-Ischemic Inflammatory Response.

Niek J Pluijmert, Rob C M de Jong, Margreet R de Vries, Knut Pettersson, Douwe E Atsma, J Wouter Jukema, Paul H A Quax

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Basic to translational science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Niek J PluijmertDepartment of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
Rob C M de JongDepartment of Surgery, Leiden University Medical Center, Leiden, the Netherlands.
Margreet R de VriesDepartment of Surgery, Leiden University Medical Center, Leiden, the Netherlands.
Knut PetterssonAthera Biotechnologies, Stockholm, Sweden.
Douwe E AtsmaDepartment of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
J Wouter JukemaDepartment of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
Paul H A QuaxDepartment of Surgery, Leiden University Medical Center, Leiden, the Netherlands.
Leiden University Medical Center · NLAthera (Sweden) · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphorylcholine monoclonal immunoglobulin G antibody attenuates the immediate post-ischemic inflammatory response by reducing the proinflammatory chemokine (C-C motif) ligand 2 chemokine and circulating Ly-6C

Indexed as

cardiac functionCCL2, chemokine (C-C motif) ligand 2CMR, cardiac magnetic resonanceEDV, end-diastolic volumeEF, ejection fractionESV, end-systolic volumeIg, immunoglobulininfarct sizeinflammationIS, infarct sizeLV, left ventricular/ventricleMI, myocardial infarctionMI-R, myocardial ischemia-reperfusionmyocardial infarctionmyocardial ischemia-reperfusionPC-mAb, phosphorylcholine monoclonal immunoglobulin G antibodyPC, phosphorylcholine

Identifiers

PMID33426378
PMCPMC7775955
OpenAlexW3108555966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.