Evidence map›Paper›PMID 33426212›Full record

ArticleRegenerative therapy2020

Inorganic polyphosphate in platelet rich plasma accelerates re-epithelialization

Bonnie C Carney, Cynthia M Simbulan-Rosenthal, Anirudh Gaur, Benjamin J Browne, Manish Moghe, Elliott Crooke, Lauren T Moffatt, Jeffrey W Shupp, Dean S Rosenthal

Open access · goldAbstract read
In one paragraph

Article in Regenerative therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Effects of Polyphosphate on Leukocyte Function.Progress in molecular and subcellular biology · 2022
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Bonnie C CarneyDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Cynthia M Simbulan-RosenthalDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Anirudh GaurDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Benjamin J BrowneFirefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, USA.
Manish MogheDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Elliott CrookeDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Lauren T MoffattDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Jeffrey W ShuppDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Dean S RosenthalDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, USA.
Georgetown University · USMedStar Health · USMedStar Washington Hospital Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing requires well-coordinated events including hemostasis, inflammation, proliferation, and remodeling. Delays in any of these stages leads to chronic wounds, infections, and hypertrophic scarring. Burn wounds are particularly problematic, and may require intervention to ensure timely progression to reduce morbidity and mortality. To accelerate burn wound healing, Platelet-Rich Plasma (PRP)

Indexed as

endopolyphosphatase, PPNepidermal growth factor, EGFexopolyphosphatase, PPXhuman foreskin fibroblasts, HFFInorganic polyphosphateKeratinocytesmammalian target of rapamycin, mTORplatelet-derived growth factor, PDGFplatelet-poor plasma, PPPplatelet-rich plasma, PRPpolyphosphates, polyPpolyP kinase, PPKPPX1 exopolyphosphatasereactive oxygen species, ROStotal body surface area, TBSAtransforming growth factor beta, TGFβvacuolar transporter chaperone 4, VTC4Wound healing

Identifiers

PMID33426212
PMCPMC7770352
OpenAlexW3047791177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.