Evidence map›Paper›PMID 33426207›Full record

ArticleRegenerative therapy2020

Collagenase treatment of cartilaginous matrix promotes fusion of adjacent cartilage.

Ching-Chuan Jiang, Chang-Hsun Hsieh, Chun-Jen Liao, Wen-Hsiang Chang, Wei-Ju Liao, Jyy-Jih Tsai-Wu, Hongsen Chiang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ching-Chuan JiangDepartment of Orthopaedic Surgery, Fu Jen Catholic University Hospital, Taipei, Taiwan.
Chang-Hsun HsiehGenomics Research, Academia Sinica, Taipei, Taiwan.
Chun-Jen LiaoTaiwan Biomaterial Co., Ltd., Taipei, Taiwan.
Wen-Hsiang ChangTaiwan Biomaterial Co., Ltd., Taipei, Taiwan.
Wei-Ju LiaoTaiwan Biomaterial Co., Ltd., Taipei, Taiwan.
Jyy-Jih Tsai-WuDepartment of Medical Research, National Taiwan University Hospital, Taipei, Taiwan.
Hongsen ChiangDepartment of Orthopaedic Surgery, National Taiwan University Hospital, Taipei, Taiwan.
National Taiwan University Hospital · TWFu Jen Catholic University · TWGenomics Research Center, Academia Sinica · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In articular cartilage-repair, grafts usually fuse unsatisfactorily with surrounding host cartilage. Enzymatic dissociation of cartilaginous matrix to free chondrocytes may benefit fusion. We tested such a hypothesis with human cartilage

Indexed as

Cartilage fusionCartilage repairCartilaginous matrixcDNA, complementary deoxyribonucleic acidDMMB, 1,9-dimethyl methylene blueDNA, deoxyribonucleic acidEnzymatic treatmentGAG, glycosaminoglycanGAPDH, glyceraldehyde 3-phosphate dehydrogenaseH&E, hematoxylin and eosinPBS, phosphate-buffered salinePCR, polymerase chain reactionRNA, ribonucleic acidSox 9, SRY-box transcription factor 9

Identifiers

PMID33426207
PMCPMC7770344
OpenAlexW3045874638

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.