ArticleRegenerative therapy2020
Osteochondral regeneration using scaffold-free constructs of adipose tissue-derived mesenchymal stem cells made by a bio three-dimensional printer with a needle-array in rabbits.
Article in Regenerative therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Promotion of bone-tendon healing after ACL reconstruction using scaffold-free constructs comprising ADSCs produced by a bio-3D printer in rabbit models.Journal of orthopaedic translation · 2025Article
- Bio-3D printing of scaffold-free ADSC-derived cartilage constructs comparable to natural cartilage in vitro.Journal of orthopaedic surgery and research · 2025Article
- Research advance of 3D printing for articular cartilage regeneration.Regenerative medicine · 2025Review
- Bioceramic-mediated chondrocyte hypertrophy promotes calcified cartilage formation for rabbit osteochondral defect repair.Bioactive materials · 2024Article
- Employing novel biocompatible composite scaffolds with bioglass 58S and poly L-lactic acid for effective bone defect treatment.Molecular biology reports · 2024Article
- Fabrication of fully aligned self-assembled cell-laden collagen filaments for tissue engineeringBioactive materials · 2024Article
- Progress in Osteochondral Regeneration with Engineering Strategies.Annals of biomedical engineering · 2022Review
- Implication of Mesenchymal Stem Cells and Their Derivates for Osteochondral Regeneration.International journal of molecular sciences · 2022Review
- Advances in Engineered Three-Dimensional (3D) Body Articulation Unit Models.Drug design, development and therapy · 2022Review
- Cell and Cell Free Therapies in Osteoarthritis.Biomedicines · 2021Review
- Emerging Biofabrication Techniques: A Review on Natural Polymers for Biomedical Applications.Polymers · 2021Review
- Potential of Exosomes as Cell-Free Therapy in Articular Cartilage Regeneration: A Review.International journal of nanomedicine · 2021Review
- Scaffold-Dependent Mechanical and Architectural Cues Guide Osteochondral Defect HealingFrontiers in bioengineering and biotechnology · 2021Article
- Current Advances in 3D Bioprinting Technology and Its Applications for Tissue Engineering.Polymers · 2020Review
- Biofabrication of the osteochondral unit and its applications: Current and future directions for 3D bioprinting.Journal of tissue engineeringReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis is a major joint disease for which medical interventions have been extensively investigated in humans and animals. In this study, we examined the regeneration of articular cartilage and subchondral bone using a scaffold-free construct consisting of adipose tissue-derived mesenchymal stem cells (AT-MSCs) fabricated using a bio three-dimensional (3D) printer. AT-MSCs were isolated from three rabbits and cultured to a number of sufficient for creation of 3D-printed constructs. One construct consisted of 960 spheroids obtained from 3.5 × 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.