Evidence map›Paper›PMID 33426202›Full record

ArticleRegenerative therapy2020

Isolation and characterization of neural crest-like progenitor cells in human umbilical cord blood.

Zena Al-Bakri, Mika Ishige-Wada, Noboru Fukuda, Chikako Yoshida-Noro, Narihito Nagoshi, Hideyuki Okano, Hideo Mugishima, Taro Matsumoto

Open access · goldAbstract read
In one paragraph

Article in Regenerative therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Zena Al-BakriDepartment of Functional Morphology, Division of Cell Regeneration and Transplantation, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Mika Ishige-WadaDepartment of Pediatrics, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Noboru FukudaDepartment of Functional Morphology, Division of Cell Regeneration and Transplantation, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Chikako Yoshida-NoroDepartment of Functional Morphology, Division of Cell Regeneration and Transplantation, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Narihito NagoshiDepartment of Orthopedic Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Hideyuki OkanoDepartment of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Hideo MugishimaDepartment of Pediatrics, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Taro MatsumotoDepartment of Functional Morphology, Division of Cell Regeneration and Transplantation, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Nihon University · JPKeio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeural crest (NC)-like stem/progenitor cells provide an attractive cell source for regenerative medicine because of their multipotent property and ease of isolation from adult tissue. Although human umbilical cord blood (HUCB) is known to be a rich source of stem cells, the presence of the NC-like stem/progenitor cells in HUCB remains to be elucidated. In this study, we have isolated NC-like progenitor cells using an antibody to p75 neurotrophin receptor (p75NTR) and examined their phenotype and stem cell function in vitro.

methodsTo confirm whether p75NTR

resultsNC-derived EGFP

conclusionsThese findings revealed that HUCB contained the p75NTR

Indexed as

Cell therapyNeural crest stem cellsp75 neurotrophin receptorUmbilical cord blood

Identifiers

PMID33426202
PMCPMC7770357
OpenAlexW3043214413

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.