Evidence map›Paper›PMID 33426065›Full record

ArticleBioMed research international2020

Association of Toll-Like Receptor 4 Gene Polymorphisms with Acute Aortic Dissection in a Chinese Han Population.

Tan Li, Xiaozheng Liu, Hongxia Ning, Xintong Li, Jun Yang, Chunyan Ma

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tan LiDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, China.ORCID https://orcid.org/0000-0002-2581-8808
Xiaozheng LiuDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, China.ORCID https://orcid.org/0000-0001-6920-2506
Hongxia NingDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, China.ORCID https://orcid.org/0000-0001-9739-4912
Xintong LiDepartment of Vascular and Thyroid Surgery, The First Hospital of China Medical University, Shenyang 110001, China.ORCID https://orcid.org/0000-0003-0873-8723
Jun YangDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, China.ORCID https://orcid.org/0000-0002-3007-4313
Chunyan MaDepartment of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang 110001, China.ORCID https://orcid.org/0000-0002-3327-736X
First Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammation may be involved in the pathogenesis of acute aortic dissection (AAD). Toll-like receptor 4 (

methodsA total of 222 AAD patients and 222 controls were enrolled in this study. Frequency distributions of

resultsWe found that rs10759932 polymorphism was associated with a reduced risk of AAD in the overall population (CC vs. TT: OR = 0.393, 95%CI = 0.164-0.939,

conclusionsOur findings provide evidence for the association between

Indexed as

Aortic AneurysmAortic DissectionAdultAgedAortaCase-Control StudiesChinaFemaleGene-Environment InteractionHumansMaleMiddle AgedPolymorphism, Single NucleotideToll-Like Receptor 4TLR4 protein, humanToll-Like Receptor 4

Identifiers

PMID33426065
PMCPMC7783515
OpenAlexW3113258170

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.