Evidence map›Paper›PMID 33426020›Full record

ArticleFrontiers in veterinary science2020

Gene Expression of Metalloproteinases and Endogenous Inhibitors in the Lamellae of Dairy Heifers With Oligofructose-Induced Laminitis.

Jiafeng Ding, Mingxian Shi, Long Wang, Dongdong Qi, Ze Tao, Muhammad A Hayat, Tao Liu, Jian-Tao Zhang, Hongbin Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Association BetweenAnimals : an open access journal from MDPI · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jiafeng DingDepartment of Veterinary Surgery, Northeast Agricultural University, Harbin, China.
Mingxian ShiDepartment of Veterinary Surgery, Northeast Agricultural University, Harbin, China.
Long WangDepartment of Veterinary Surgery, Northeast Agricultural University, Harbin, China.
Dongdong QiDepartment of Veterinary Surgery, Northeast Agricultural University, Harbin, China.
Ze TaoDepartment of Veterinary Surgery, Northeast Agricultural University, Harbin, China.
Muhammad A HayatDepartment of Veterinary Surgery, Northeast Agricultural University, Harbin, China.
Tao LiuDepartment of Veterinary Surgery, Northeast Agricultural University, Harbin, China.
Jian-Tao ZhangDepartment of Veterinary Surgery, Northeast Agricultural University, Harbin, China.
Hongbin WangDepartment of Veterinary Surgery, Northeast Agricultural University, Harbin, China.
Education Department of Heilongjiang Province · CNNortheast Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine laminitis leads to huge economic losses and animal welfare problems in the dairy industry worldwide. Numerous studies suggested that several metalloproteinases (MPs) may play vital roles in the failure of epidermal attachment. To the best of our knowledge, the present study is the first to investigate and characterize the gene-level changes in distinct MPs and endogenous inhibitors using oligofructose (OF)-induced bovine laminitis model. The objective of this study was to determine aberrant MPs and related inhibitors of bovine laminitis in gene level, and to provide reasonable directions for the further protein-level research. Twelve normal Chinese Holstein dairy heifers were randomly divided into treatment group (

Indexed as

bovine laminibovine laminitismetalloproteinaseoligofructose overload modelpathogenesisreal-time quantitative PCRTIMP

Identifiers

PMID33426020
PMCPMC7786368
OpenAlexW3114962720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.