Evidence map›Paper›PMID 33425881›Full record

ReviewFrontiers in bioengineering and biotechnology2020

Current Trends of Targeted Drug Delivery for Oral Cancer Therapy.

Mingming Zhang, Jianqin Liang, Yanyu Yang, Huize Liang, Huaping Jia, Dawei Li

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

  1. Pooled it
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  10. The Role and Advancement of Liposomes for Oral Diseases Therapy.International journal of nanomedicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mingming ZhangStrategic Support Force Characteristic Medical Center of Chinese People's Liberation Army, Beijing, China.
Jianqin LiangThe 8th Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing, China.
Yanyu YangCollege of Materials Science and Engineering, Zhengzhou University, Zhengzhou, China.
Huize LiangStrategic Support Force Characteristic Medical Center of Chinese People's Liberation Army, Beijing, China.
Huaping JiaStrategic Support Force Characteristic Medical Center of Chinese People's Liberation Army, Beijing, China.
Dawei LiThe 4th Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing, China.
Chinese People's Liberation Army · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer is an aggressive tumor that invades the local tissue and can cause metastasis and high mortality. Conventional treatment strategies, e.g., surgery, chemotherapy, and radiation therapy alone or in combinations, possess innegligible issues, and significant side and adverse effects for the clinical applications. Currently, targeting drug delivery is emerging as an effective approach for oral delivery of different therapeutics. Herein we provide a state-of-the-art review on the current progress of targeting drug delivery for oral cancer therapy. Variously oral delivery systems including polymeric/inorganic nanoparticles, liposomes, cyclodextrins, nanolipids, and hydrogels-based forms are emphasized and discussed, and biomimetic systems with respect to oral delivery like therapeutic vitamin, exosomes, proteins, and virus-like particles are also described with emphasis on the cancer treatment. A future perspective is also provided to highlight the existing challenges and possible resolution toward clinical translation of current oral cancer therapies.

Indexed as

drug deliverynanoparticlesnanotechnologyoral cancerOSCC (oral squamous cell carcinoma)

Identifiers

PMID33425881
PMCPMC7793972
OpenAlexW3112915773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.