ArticleCanadian journal of gastroenterology & hepatology2020
The Prevalence, Predictors, and In-Hospital Mortality of Hepatic Encephalopathy in Patients with Liver Cirrhosis Admitted at St. Dominic Hospital in Akwatia, Ghana.
Article in Canadian journal of gastroenterology & hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Prevalence of hepatitis C viral infection in Ghana: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Embolization of spontaneous portosystemic shunts for refractory hepatic encephalopathy in cirrhosis patients:A meta-analysis.Hepatology forum · 2026Review
- Machine learning-based risk prediction of overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with cirrhosis: a cohort study.Frontiers in medicine · 2026Article
- Article
- Predictors of Mortality in Patients with Hepatic Encephalopathy: A Retrospective Analysis.Cureus · 2025Article
- Effects of Timing of Endoscopy on Clinical Outcomes of Cirrhotic Patients with Acute Variceal Bleeding in a Tertiary Hospital.Acta medica Philippina · 2025Article
- Predictors of in-hospital mortality among cirrhotic patients in Ethiopia: A multicenter retrospective study.PloS one · 2025Observational
- Linking Brain and Immune Transcriptomes to Gut-Derived Metabolites in Hepatic Encephalopathy: An Explorative Integrative Multi-Omics Approach.Hepatic medicine : evidence and research · 2025Article
- Interpretable machine learning model for predicting covert hepatic encephalopathy in patients with cirrhosis: a multicenter study.Frontiers in medicine · 2025Article
- The Balance of Ketoacids α-Ketoglutarate and α-Ketoglutaramate Reflects the Degree of the Development of Hepatoencephalopathy in Rats.International journal of molecular sciences · 2024Review
- A Novel Scoring System for Assessing In-Hospital Mortality Risk in Patients With Liver Cirrhosis.Cureus · 2024Article
- [A nomogram prediction model for individualized prediction of the risk of covert (minimal) hepatic encephalopathy occurrence in patients with liver cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024Article
- Serum zinc level in liver cirrhosis with hepatic encephalopathy and its correlation with different stages of hepatic encephalopathy.Journal of family medicine and primary care · 2024Article
- Assessment of gnostic and stereognostic functions in patients with liver cirrhosis: A comparative study with healthy controls.Journal of back and musculoskeletal rehabilitation · 2024Article
- Hepatic Encephalopathy among Patients with Chronic Liver Disease Admitted to the Department of Internal Medicine in a Tertiary Care Centre: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2023Article
- Factors Associated with in-Hospital Mortality in Malagasy Patients with Acute Decompensation of Liver Cirrhosis: A Retrospective Cohort.Hepatic medicine : evidence and research · 2023Article
- Sociodemographic and medical characteristics of liver cirrhosis deaths in a Ghanaian tertiary hospital.Ghana medical journal · 2022Article
- Article
- Prediction and Risk Factors for Prognosis of Cirrhotic Patients with Hepatic Encephalopathy.Gastroenterology research and practice · 2021Article
- Recurrence of portosystemic encephalopathy in cirrhotic patients and its risk factors.Pakistan journal of medical sciencesArticle
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hepatic encephalopathy (HE) is one of the most debilitating complications of cirrhosis leading to death. Decrease in HE mortality and recurrence has been linked with timely identification and early treatment. There is a need to document the burden, predictors, and treatment outcomes of HE in an adult population with liver cirrhosis in our setting as only reports from resource-endowed countries abound in the literature. This study aimed therefore to determine the prevalence, predictors, and treatment outcomes of patients with liver cirrhosis admitted at St. Dominic Hospital (SDH) in Akwatia, Ghana. Materials and Methods: A prospective study was conducted involving one hundred and sixty-seven (167) patients admitted at the medical wards in SDH with liver cirrhosis from January 1st, 2018, to March 24th, 2020. The demographic and clinical features of the patients were collected using a standardized questionnaire. Biochemical, haematological, and abdominal ultrasound scans were done for all patients. Patients were then followed up until discharge or death. Results: There were 109 (65.3%) males out of the 167 patients with a mean age of 45.8 and 47.5 years for those with and without HE, respectively. The prevalence of HE was 31.7% (53/167). Out of 53 participants with HE, 75.5% (40/53) died. There was a strong association between HE and death ( Conclusion: HE was common among patients with liver cirrhosis admitted at SDH with high in-patient mortality. The commonest precipitating factor for HE was infection(s). Severe ascites, low platelet count, high creatinine, BUN, and CPS were independent predictors of HE.
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