Evidence map›Paper›PMID 33425777›Full record

ArticleFrontiers in cellular and infection microbiology2020

Human Short Peptidoglycan Recognition Protein PGLYRP1/Tag-7/PGRP-S Inhibits

Darya Slonova, Alexandra Posvyatenko, Alexey Kibardin, Elena Sysolyatina, Elena Lyssuk, Svetlana Ermolaeva, Sergei Obydennyi, Nikolay Gnuchev, Georgii Georgiev, Konstantin Severinov and 1 more

Open access · goldAbstract read
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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Darya SlonovaLaboratory of Molecular Microbiology, Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russia.
Alexandra PosvyatenkoLaboratory of Molecular Immunology, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Russian Ministry of Health, Moscow, Russia.
Alexey KibardinLaboratory of Molecular Immunology, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Russian Ministry of Health, Moscow, Russia.
Elena SysolyatinaLaboratory of Ecology of Pathogenic Bacteria, Gamaleya National Research Centre of Epidemiology and Microbiology, Russian Ministry of Health, Moscow, Russia.
Elena LyssukLaboratory of Molecular Immunology, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Russian Ministry of Health, Moscow, Russia.
Svetlana ErmolaevaLaboratory of Ecology of Pathogenic Bacteria, Gamaleya National Research Centre of Epidemiology and Microbiology, Russian Ministry of Health, Moscow, Russia.
Sergei ObydennyiLaboratory of Intracellular Signaling and Systems Biology, Centre for Theoretical Problems of Physicochemical Pharmacology, Moscow, Russia.
Nikolay GnuchevLaboratory of Cancer Immunogenetics, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
Georgii GeorgievLaboratory of Cancer Immunogenetics, Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia.
Konstantin SeverinovLaboratory of Molecular Microbiology, Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russia.
Sergey LarinLaboratory of Molecular Immunology, Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Russian Ministry of Health, Moscow, Russia.
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology · RUInstitute of Gene Biology · RUMinistry of Health of the Russian Federation · RUSkolkovo Institute of Science and Technology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PGLYRP1/Tag-7/PGRP-S is one of mammalian peptidoglycan recognition proteins (PGRPs). Here, we demonstrate that human recombinant PGLYRP1/Tag-7/PGRP-S potentiates the response of murine macrophage-like ANA-1 cells and human macrophages to facultative intracellular pathogen

Indexed as

CytokinesIntracellular SpaceListeria monocytogenesListeriosisMacrophagesMicrobial ViabilityAnimalsCell LineHumansMicePhagocytosisRespiratory BurstCytokinesPGLYRP1 protein, humaninnate immunityListeria monocytogenespeptidoglycan recognition proteinpeptidoglycan recognition protein-SPGLYRP1 proteinphagocytosisTag-7

Identifiers

PMID33425777
PMCPMC7785527
OpenAlexW3116009979

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.