Evidence map›Paper›PMID 33425714›Full record

ArticleFrontiers in oncology2020

The Esophageal Adenocarcinoma Epidemic Has Reached Hungary: A Multicenter, Cross-Sectional Study.

Benedek Tinusz, László Botond Szapáry, Bence Paládi, András Papp, Barna Bogner, Ivett Hegedűs, Szabolcs Bellyei, Áron Vincze, Jenő Solt, Tamás Micsik and 8 more

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Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effects of neoadjuvant chemotherapyWorld journal of gastroenterology · 2024
    Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Benedek TinuszMedical School, Institute for Translational Medicine and Szentágothai Research Center, University of Pécs, Pécs, Hungary.
László Botond SzapáryMedical School, Institute for Translational Medicine and Szentágothai Research Center, University of Pécs, Pécs, Hungary.
Bence PaládiMedical School, Institute for Translational Medicine and Szentágothai Research Center, University of Pécs, Pécs, Hungary.
András PappDepartment of Surgery, University of Pécs, Pécs, Hungary.
Barna BognerDepartment of Pathology, Medical School, University of Pécs, Pécs, Hungary.
Ivett HegedűsDepartment of Pathology, Medical School, University of Pécs, Pécs, Hungary.
Szabolcs BellyeiDepartment of Oncotherapy, Medical School, University of Pécs, Pécs, Hungary.
Áron VinczeDepartment of Gastroenterology, 1st Department of Medicine, Medical School, University of Pécs, Pécs, Hungary.
Jenő SoltDepartment of Gastroenterology, 1st Department of Medicine, Medical School, University of Pécs, Pécs, Hungary.
Tamás Micsik1st Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
Veronika Dunás-Varga1st Department of Internal Medicine, Szent György University Teaching Hospital of Fejér County, Székesfehérvár, Hungary.
Eszter Pályu2nd Department of Internal Medicine, University of Debrecen, Debrecen, Hungary.
Tamás Vass1st Department of Surgery, Semmelweis University, Budapest, Hungary.
Tamás SchnabelDepartment of Gastroenterology, Saint John's Hospital, Budapest, Hungary.
Nelli FarkasMedical School, Institute of Bioanalysis, University of Pécs, Pécs, Hungary.
Péter HegyiMedical School, Institute for Translational Medicine and Szentágothai Research Center, University of Pécs, Pécs, Hungary.
Aaron P ThriftDepartment of Medicine and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, United States.
Bálint ErőssMedical School, Institute for Translational Medicine and Szentágothai Research Center, University of Pécs, Pécs, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe epidemiology of esophageal cancer has changed dramatically over the past 4 decades in many Western populations. We aimed to understand the Hungarian epidemiologic trends of esophageal squamous cell cancer (SCC) and adenocarcinoma (AC).

methodsWe performed a cross-sectional study using data from esophageal cancer patients diagnosed between 1992 and 2018 at eight tertiary referral centers in four major cities of Hungary. We retrospectively identified cases in the electronic databases of each center and collected data on gender, age at diagnosis, year of diagnosis, specialty of the origin center, histological type, and localization of the tumor. Patients were grouped based on the two main histological types: AC or SCC. For statistical analysis, we used linear regression models, chi-square tests, and independent sample t tests.

resultsWe extracted data on 3,283 patients with esophageal cancer. Of these, 2,632 were diagnosed with either of the two main histological types; 737 had AC and 1,895 SCC. There was no significant difference in the gender ratio of the patients between AC and SCC (80.1

conclusionsThe rapid increase in the relative incidence of AC and simultaneous decrease of the relative incidence of SCC suggest that this well-established Western phenomenon is also present in Hungary.

Indexed as

cancerepidemiologyesophageal adenocarcinomaesophageal canceresophagusincidenceoncology

Identifiers

PMID33425714
PMCPMC7786275

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.