Evidence map›Paper›PMID 33425692›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2021

De novo expression and antibacterial potential of four lactoferricin peptides in cell-free protein synthesis system.

Nawal Abd El-Baky, Maie Ahmed Elkhawaga, Eman Shawky Abdelkhalek, Mona Mohammed Sharaf, Elrashdy Mustafa Redwan, Hoda Reda Kholef

Open access · goldAbstract read
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nawal Abd El-BakyTherapeutic and Protective Proteins Laboratory, Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications, New Borg EL-Arab, 21934, Alexandria, Egypt.
Maie Ahmed ElkhawagaBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
Eman Shawky AbdelkhalekBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Cairo, Egypt.
Mona Mohammed SharafTherapeutic and Protective Proteins Laboratory, Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications, New Borg EL-Arab, 21934, Alexandria, Egypt.
Elrashdy Mustafa RedwanTherapeutic and Protective Proteins Laboratory, Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications, New Borg EL-Arab, 21934, Alexandria, Egypt.
Hoda Reda KholefTherapeutic and Protective Proteins Laboratory, Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications, New Borg EL-Arab, 21934, Alexandria, Egypt.
City of Scientific Research and Technological Applications · EGAl-Azhar University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the first time, we produced four lactoferricin (LFcin) peptides by a cell-free (

Indexed as

3D, three dimensional structuresAntimicrobialBioactive peptidesbLFcin, bovine lactoferricinCAMH, cation-adjusted Mueller-Hinton brothCFPS, cell-free protein synthesiscLf, camel lactoferrincLFcin, camel lactoferricinConLFcin, consensus lactoferricinELISA, enzyme-linked immunosorbent assayhLFcin, human lactoferricinhLf, human lactoferrinHSV, herpes simplex virusIn vitro protein synthesisLactoferricinLactoferrinLC50, concentration lethal to 50 % of the cellsLFcin, lactoferricinLf, lactoferrinMIC, minimum inhibitory concentrationMICs, minimum inhibitory concentrationsMRSA, methicillin-resistant Staphylococcus aureusPBMCs, peripheral blood mononuclear cellsp-NPP, p-Nitrophenyl phosphateSD, Shine-Dalgarno sequenceSDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis

Identifiers

PMID33425692
PMCPMC7779732
OpenAlexW3117662497

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.